A New Pyrone from a Marine-Derieved Fungus Penicillium sp. 108YD020

Title
A New Pyrone from a Marine-Derieved Fungus Penicillium sp. 108YD020
Author(s)
필감방; 이민아; 이화선; 최병규; 이희승; 이종석; 이연주; 신희재
KIOST Author(s)
Lee, Min Ah(이민아)Lee, Hwa Sun(이화선)Lee, Hyi Seung(이희승)Lee, Jong Seok(이종석)Lee, Yeon Ju(이연주)Shin, Hee Jae(신희재)
Alternative Author(s)
필감방; 이민아; 이화선; 최병규; 이희승; 이종석; 이연주; 신희재
Publication Year
2014-10-24
Abstract
Marine microbes, particularly fungi, have been utilized as a new source of novel bioactive secondary metabolites. Marine sponge-associated fungi are receiving increasing attention due to their biotechnological potential. They often live in sponges and their bioactive metabolites may be interpreted as chemical mediated defense mechanisms for protecting their host organism from environmental dangers such as predation. A Penicillium sp. strain 108YDC020 was isolated from an unidentified sponge collected at Wangdolcho, East sea, Korea to search for new natural products with biological activities and novel chemical structures. A new compound was obtained from the EtOAc extract of the culture broth of the strain by C-18 ODS open column and preparative and analytical HPLCs. The structure of this compound was determined by MS, 1D and 2D NMR spectral data analysis.in sponges and their bioactive metabolites may be interpreted as chemical mediated defense mechanisms for protecting their host organism from environmental dangers such as predation. A Penicillium sp. strain 108YDC020 was isolated from an unidentified sponge collected at Wangdolcho, East sea, Korea to search for new natural products with biological activities and novel chemical structures. A new compound was obtained from the EtOAc extract of the culture broth of the strain by C-18 ODS open column and preparative and analytical HPLCs. The structure of this compound was determined by MS, 1D and 2D NMR spectral data analysis.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/25912
Bibliographic Citation
The Pharmaceutical Society of Korea, pp.84, 2014
Publisher
The parmaceutical society of korea
Type
Conference
Language
English
Publisher
The parmaceutical society of korea
Files in This Item:
There are no files associated with this item.

qrcode

Items in ScienceWatch@KIOST are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse