Tetracenomycins, Antimicrobial Compounds Isolated From a Marine Streptomyces sp.

Title
Tetracenomycins, Antimicrobial Compounds Isolated From a Marine Streptomyces sp.
Author(s)
최병규; 이화선; 필감방; 이희승; 이종석; 이연주; 이지훈; 신희재
KIOST Author(s)
Choi, Byeoung Kyu(최병규)Lee, Hwa Sun(이화선)Lee, Hyi Seung(이희승)Lee, Jong Seok(이종석)Lee, Yeon Ju(이연주)Lee, Jihoon(이지훈)
Publication Year
2016-04-22
Abstract
Marine-derived microorganisms are an interesting source for valuable secondary metabolites. Moreover, many natural products from marine microbes were developed as medicines and are being studied to cure incurable diseases and diverse infections. Especially, species of Streptomyces have been received significant attention since they produce unexpected and unusual chemical compounds with notable biological activities. The strain 151KO-065 was isolated from a mangrove tree stump collected in Kosrae island, Micronesia and identified as Streptomyces sp. From this strain, two novel compounds, tetracenomycin C and 8-demethoxytetracenomycin C, were isolated from the EtOAc extract of the culture broth (60L). Their structures were determined by MS and 2D NMR data analyses.tions. Especially, species of Streptomyces have been received significant attention since they produce unexpected and unusual chemical compounds with notable biological activities. The strain 151KO-065 was isolated from a mangrove tree stump collected in Kosrae island, Micronesia and identified as Streptomyces sp. From this strain, two novel compounds, tetracenomycin C and 8-demethoxytetracenomycin C, were isolated from the EtOAc extract of the culture broth (60L). Their structures were determined by MS and 2D NMR data analyses.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/24854
Bibliographic Citation
The Korean Society for Biotechnology and Bioengineering, pp.128, 2016
Publisher
The KOREAN SOCIETY FOR BIOTECHNOLOGY AND BIOENGINEERING
Type
Conference
Language
English
Publisher
The KOREAN SOCIETY FOR BIOTECHNOLOGY AND BIOENGINEERING
Related Researcher
Research Interests

Marine Natural Products,Organic Chemistry,해양천연물,유기화학

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