Isolation and Identification of Prenylated Phenols and Prenylated Indole Diketopiperazine Alkaloids from Aspergillus chevalieri 168CLC-47.2

Title
Isolation and Identification of Prenylated Phenols and Prenylated Indole Diketopiperazine Alkaloids from Aspergillus chevalieri 168CLC-47.2
Author(s)
최병규; 이화선; 이희승; 이종석; 이연주; 이지훈; 신희재
KIOST Author(s)
Choi, Byeoung Kyu(최병규)Lee, Hwa Sun(이화선)Lee, Hyi Seung(이희승)Lee, Jong Seok(이종석)Lee, Yeon Ju(이연주)Lee, Jihoon(이지훈)
Publication Year
2018-10-18
Abstract
Marine-derived microorganisms, especially marine fungi, are an interesting source for marine natural product researches. Moreover, many natural products from marine fungi were developed as medicines and are being studied to cure diverse diseases and infections. Especially, species of Aspergillus have been received significant attention since they produce unexpected and unusual chemical compounds with notable biological activities such as antibacterial, antifungal, antitumor,antiviral activities. The fungus 168CLC-47.2 was isolated from an unidentified soft coral, collected at Cu Lao Cham island, Quang Nam, Vietnam by modified Sabouraud medium and identified as Aspergillus chevalieri. From the strain, prenylated phenol derivates and prenylated indole diketopiperazine alkaloids were isolated from the EtOAc extract. Their structures were determined by MS, 1D and 2D NMR data analyses.eases and infections. Especially, species of Aspergillus have been received significant attention since they produce unexpected and unusual chemical compounds with notable biological activities such as antibacterial, antifungal, antitumor,antiviral activities. The fungus 168CLC-47.2 was isolated from an unidentified soft coral, collected at Cu Lao Cham island, Quang Nam, Vietnam by modified Sabouraud medium and identified as Aspergillus chevalieri. From the strain, prenylated phenol derivates and prenylated indole diketopiperazine alkaloids were isolated from the EtOAc extract. Their structures were determined by MS, 1D and 2D NMR data analyses.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/23030
Bibliographic Citation
The Pharmaceutical Society of Korea, pp.323, 2018
Publisher
The Pharmaceutical Society of Korea
Type
Conference
Language
English
Publisher
The Pharmaceutical Society of Korea
Related Researcher
Research Interests

Marine Natural Products,Organic Chemistry,해양천연물,유기화학

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