The isolation and structure elucidation of compounds isolated from marine Mollusca collected in Jeju-island

Title
The isolation and structure elucidation of compounds isolated from marine Mollusca collected in Jeju-island
Author(s)
김수현; 이연주
KIOST Author(s)
Lee, Yeon Ju(이연주)
Publication Year
2018-10-18
Abstract
Five compounds were isolated from Reisshia clavigera collected in Jeju-island, Republic of Korea. As far as we have searched, there have been no previous reports regarding the secondary metabolites isolated from these species. The structures of isolated compounds were elucidated based on the analysis by NMR and HRMS and they could be identified to be oxazinin-1, 2, tyrindoxyl sulfate, homarine, chimyl alcohol, and 3-hydroxypiperidine-2-one. The growth inhibitory activities of those compounds against several cancer cell lines are now under investigation.s of isolated compounds were elucidated based on the analysis by NMR and HRMS and they could be identified to be oxazinin-1, 2, tyrindoxyl sulfate, homarine, chimyl alcohol, and 3-hydroxypiperidine-2-one. The growth inhibitory activities of those compounds against several cancer cell lines are now under investigation.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/23028
Bibliographic Citation
Archives of Pharmacal Research, pp.339, 2018
Publisher
Archives
Type
Conference
Language
English
Publisher
Archives
Related Researcher
Research Interests

Marine Natural Product,Natural Product Biosynthesis,Medicinal Chemistry,해양 천연물,천연물 생합성,의약화학

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