노닐페놀을 주사한 조피볼락의 간장 cytochrome P450과 EROD의 반응 KCI OTHER

DC Field Value Language
dc.contributor.author 전중균 -
dc.contributor.author 이지선 -
dc.contributor.author 손영창 -
dc.contributor.author 심원준 -
dc.contributor.author 정지현 -
dc.contributor.author 홍경표 -
dc.contributor.author 김병기 -
dc.contributor.author 한창희 -
dc.date.accessioned 2020-04-20T15:25:18Z -
dc.date.available 2020-04-20T15:25:18Z -
dc.date.created 2020-02-10 -
dc.date.issued 2004-03 -
dc.identifier.issn 1226-9999 -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/5277 -
dc.description.abstract Nonyphenol (NP) used actively as non -ionic surfactant is classified as oneof most potent endocrine disrupting chemicals. Effects of NP on mixed functionoxygenase (MFO) system in rockfish ( Sebastes schlegeli ) were investigated for sevendays after intraperitoneal injection (10 and 25 mg kg-1). Hepatosomatic index (HSI) offishes exposed to NP of 25 mg kg-1 was significantly reduced compared to those incontrol group. NP exposure enhanced cytochrome P450 levels in the fish liver, while 7 -ethoxyresorufin -O-deethylase (EROD) activity was inhibited. NP exposure levels inthis study were much higher than those found in the coastal environment of Korea.Effects on HSI and liver MFO system, which is involved in steroid hormone metab-olism, imply that NP may influence on reproduction of fish by not only hormone recep-tor mediated response but also through effects on the MFO system. -
dc.description.uri 2 -
dc.publisher 한국환경생물학회 -
dc.title 노닐페놀을 주사한 조피볼락의 간장 cytochrome P450과 EROD의 반응 -
dc.title.alternative Responses of Cytochrome P450 and EROD Activity in Rockfish (Paralichthys olivaceus) Administered Intraperitoneal Injection of 4-nonylphenol -
dc.type Article -
dc.citation.endPage 176 -
dc.citation.startPage 171 -
dc.citation.title 환경생물 -
dc.citation.volume 22 -
dc.citation.number 1 -
dc.identifier.bibliographicCitation 환경생물, v.22, no.1, pp.171 - 176 -
dc.identifier.kciid ART001158562 -
dc.description.journalClass 2 -
dc.description.isOpenAccess N -
dc.subject.keywordAuthor 4-nonylphenol -
dc.subject.keywordAuthor rockfish -
dc.subject.keywordAuthor Sebastes schlegeli -
dc.subject.keywordAuthor cytochrome P450 -
dc.subject.keywordAuthor EROD -
dc.subject.keywordAuthor hepatosomatic index -
dc.description.journalRegisteredClass kci -
dc.description.journalRegisteredClass other -
Appears in Collections:
South Sea Research Institute > Risk Assessment Research Center > 1. Journal Articles
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