Enhanced Photosynthetic Pigment Production Using a Scaled-Up Continuously Circulated Bioreactor
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Title
- Enhanced Photosynthetic Pigment Production Using a Scaled-Up Continuously Circulated Bioreactor
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Author(s)
- Lee, Won Kyu; Ryu, Yong Kyun; Kim, Tae Ho; Park, Areumi; Lee, Yeon-Ji; Sunwoo, In Yung; Koh, Eun-Jeong; Oh, Chul Hong; Choi, Yong Woon; Kang, Do Hyung
- KIOST Author(s)
- Lee, Won-Kyu(이원규); Ryu, Yong Kyun(유용균); Kim, Tae Ho(김태호); Park, Areumi(박아름이); Lee, Yeon-Ji(이연지); null선우인영; Koh, Eun-Jeong(고은정); Oh, Chul Hong(오철홍); Choi, Yong Woon(최운용); Kang, Do Hyung(강도형)
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Alternative Author(s)
- 이원규; 유용균; 김태호; 박아름이; 이연지; 선우인영; 고은정; 오철홍; 최운용; 강도형
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Publication Year
- 2023-11
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Abstract
- Microalgae have gained attention as a promising source of chlorophylls and carotenoids in various industries. However, scaling up of conventional bubble columns presents challenges related to cell sedimentation and the presence of non-photosynthetic cells due to non-circulating zones and decreased light accessibility, respectively. Therefore, this study aimed to evaluate the newly developed continuously circulated bioreactor ROSEMAX at both laboratory and pilot scales, compared to a conventional bubble column. There was no significant difference in the biomass production and photosynthetic pigment content of Tetraselmis sp. cultivated at the laboratory scale (p > 0.05). However, at the pilot scale, the biomass cultured in ROSEMAX showed significantly high biomass (1.69 ± 0.11 g/L, dry weight, DW), chlorophyll-a (14.60 ± 0.76 mg/g, DW), and total carotene (5.64 ± 0.81 mg/g, DW) concentrations compared to the conventional bubble column (1.17 ± 0.11 g/L, DW, 10.67 ± 0.72 mg/g, DW, 3.21 ± 0.56 mg/g, DW, respectively) (p ≤ 0.05). Flow cytometric analyses confirmed that the proportion of Tetraselmis sp. live cells in the culture medium of ROSEMAX was 32.90% higher than that in the conventional bubble column, with a photosynthetic efficiency 1.14 times higher. These results support suggestions to use ROSEMAX as a bioreactor for industrial-scale applications.
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ISSN
- 1660-3397
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URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/44720
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DOI
- 10.3390/md21110576
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Bibliographic Citation
- Marine Drugs, v.21, no.11, 2023
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Publisher
- Multidisciplinary Digital Publishing Institute (MDPI)
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Keywords
- Tetraselmis sp.; photosynthetic pigment; scale-up; pilot scale; ROSEMAX
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Type
- Article
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Language
- English
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Document Type
- Article
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