Polyoxygenated Diterpenes from the Sponge Phorbas sp. SCIE SCOPUS
DC Field | Value | Language |
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dc.contributor.author | Jang, Kyoung Hwa | - |
dc.contributor.author | Jeon, Ju-eun | - |
dc.contributor.author | Ryu, Sungkwang | - |
dc.contributor.author | Lee, Hyi-Seung | - |
dc.contributor.author | Oh, Ki-Bong | - |
dc.contributor.author | Shin, Jongheon | - |
dc.date.accessioned | 2020-04-20T10:40:22Z | - |
dc.date.available | 2020-04-20T10:40:22Z | - |
dc.date.created | 2020-01-28 | - |
dc.date.issued | 2008-10 | - |
dc.identifier.issn | 0163-3864 | - |
dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/4445 | - |
dc.description.abstract | Ten new polyoxygenated diterpenes (7-16) along with six known gagunin compounds (1-6) were isolated from the sponge Phorbas sp. collected in the Korean Sea. Oil the basis of a combination of NMR and mass spectroscopic analyses, the molecular structures of these diterpenes, designated as gagunins H-Q, were determined to be penta- or hexa-oxygenated diterpenes of the 10, 13-bis-epi-homoverrucosane class. A new diterpene acid (17) of a bisabolane-related skeletal class was also isolated and structurally defined by the spectroscopic analyses. These compounds exhibited moderate to significant cytoloxicity against the K-562 cell line as well as weak inhibitory activity against isocitrate lyase (ICL). | - |
dc.description.uri | 1 | - |
dc.language | English | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.subject | AUSTRALIAN MARINE SPONGE | - |
dc.subject | MYLIA-VERRUCOSA | - |
dc.subject | A-D | - |
dc.subject | ABSOLUTE-CONFIGURATION | - |
dc.subject | LIVERWORT | - |
dc.subject | PHORBOXAZOLES | - |
dc.subject | AMARANTHUS | - |
dc.subject | MACROLIDES | - |
dc.title | Polyoxygenated Diterpenes from the Sponge Phorbas sp. | - |
dc.type | Article | - |
dc.citation.endPage | 1707 | - |
dc.citation.startPage | 1701 | - |
dc.citation.title | JOURNAL OF NATURAL PRODUCTS | - |
dc.citation.volume | 71 | - |
dc.citation.number | 10 | - |
dc.contributor.alternativeName | 이희승 | - |
dc.identifier.bibliographicCitation | JOURNAL OF NATURAL PRODUCTS, v.71, no.10, pp.1701 - 1707 | - |
dc.identifier.doi | 10.1021/np800293y | - |
dc.identifier.scopusid | 2-s2.0-56049092744 | - |
dc.identifier.wosid | 000260384400007 | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | AUSTRALIAN MARINE SPONGE | - |
dc.subject.keywordPlus | MYLIA-VERRUCOSA | - |
dc.subject.keywordPlus | A-D | - |
dc.subject.keywordPlus | ABSOLUTE-CONFIGURATION | - |
dc.subject.keywordPlus | LIVERWORT | - |
dc.subject.keywordPlus | PHORBOXAZOLES | - |
dc.subject.keywordPlus | AMARANTHUS | - |
dc.subject.keywordPlus | MACROLIDES | - |
dc.relation.journalWebOfScienceCategory | Plant Sciences | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Plant Sciences | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |