Polyoxygenated Diterpenes from the Sponge Phorbas sp. SCIE SCOPUS

DC Field Value Language
dc.contributor.author Jang, Kyoung Hwa -
dc.contributor.author Jeon, Ju-eun -
dc.contributor.author Ryu, Sungkwang -
dc.contributor.author Lee, Hyi-Seung -
dc.contributor.author Oh, Ki-Bong -
dc.contributor.author Shin, Jongheon -
dc.date.accessioned 2020-04-20T10:40:22Z -
dc.date.available 2020-04-20T10:40:22Z -
dc.date.created 2020-01-28 -
dc.date.issued 2008-10 -
dc.identifier.issn 0163-3864 -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/4445 -
dc.description.abstract Ten new polyoxygenated diterpenes (7-16) along with six known gagunin compounds (1-6) were isolated from the sponge Phorbas sp. collected in the Korean Sea. Oil the basis of a combination of NMR and mass spectroscopic analyses, the molecular structures of these diterpenes, designated as gagunins H-Q, were determined to be penta- or hexa-oxygenated diterpenes of the 10, 13-bis-epi-homoverrucosane class. A new diterpene acid (17) of a bisabolane-related skeletal class was also isolated and structurally defined by the spectroscopic analyses. These compounds exhibited moderate to significant cytoloxicity against the K-562 cell line as well as weak inhibitory activity against isocitrate lyase (ICL). -
dc.description.uri 1 -
dc.language English -
dc.publisher AMER CHEMICAL SOC -
dc.subject AUSTRALIAN MARINE SPONGE -
dc.subject MYLIA-VERRUCOSA -
dc.subject A-D -
dc.subject ABSOLUTE-CONFIGURATION -
dc.subject LIVERWORT -
dc.subject PHORBOXAZOLES -
dc.subject AMARANTHUS -
dc.subject MACROLIDES -
dc.title Polyoxygenated Diterpenes from the Sponge Phorbas sp. -
dc.type Article -
dc.citation.endPage 1707 -
dc.citation.startPage 1701 -
dc.citation.title JOURNAL OF NATURAL PRODUCTS -
dc.citation.volume 71 -
dc.citation.number 10 -
dc.identifier.bibliographicCitation JOURNAL OF NATURAL PRODUCTS, v.71, no.10, pp.1701 - 1707 -
dc.identifier.doi 10.1021/np800293y -
dc.identifier.scopusid 2-s2.0-56049092744 -
dc.identifier.wosid 000260384400007 -
dc.type.docType Article -
dc.description.journalClass 1 -
dc.subject.keywordPlus AUSTRALIAN MARINE SPONGE -
dc.subject.keywordPlus MYLIA-VERRUCOSA -
dc.subject.keywordPlus A-D -
dc.subject.keywordPlus ABSOLUTE-CONFIGURATION -
dc.subject.keywordPlus LIVERWORT -
dc.subject.keywordPlus PHORBOXAZOLES -
dc.subject.keywordPlus AMARANTHUS -
dc.subject.keywordPlus MACROLIDES -
dc.relation.journalWebOfScienceCategory Plant Sciences -
dc.relation.journalWebOfScienceCategory Chemistry, Medicinal -
dc.relation.journalWebOfScienceCategory Pharmacology & Pharmacy -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -
dc.relation.journalResearchArea Plant Sciences -
dc.relation.journalResearchArea Pharmacology & Pharmacy -
Appears in Collections:
Marine Resources Research Division > Marine Biotechnology Research Center > 1. Journal Articles
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