New Glycosylated Secondary Metabolites from Marine-Derived Bacteria SCIE SCOPUS

DC Field Value Language
dc.contributor.author Anh, Cad Van -
dc.contributor.author Kang, Jong Soon -
dc.contributor.author Lee, Hwa Sun -
dc.contributor.author Trinh, Phan Thi Hoai -
dc.contributor.author Heo, Chang Su -
dc.contributor.author Shin, Hee Jae -
dc.date.accessioned 2022-07-25T01:30:07Z -
dc.date.available 2022-07-25T01:30:07Z -
dc.date.created 2022-07-25 -
dc.date.issued 2022-07 -
dc.identifier.issn 1660-3397 -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/43101 -
dc.description.abstract Three new glycosylated secondary metabolites, including a new indole alkaloid, pityriacitrin D (1), and two new trehalose lipids (2 and 3), together with three known compounds (4–6) were isolated from two marine-derived bacterial strains, Bacillus siamensis 168CLC-66.1 and Tsukamurella pseudospumae IV19-045. The structures of 1–3 were determined by extensive analysis and comparison of their spectroscopic data with literature values. The absolute configurations of sugar moieties were determined by chemical derivatization followed by LC-MS analysis. Cytotoxicity of 1–3 against six cancer cell lines was evaluated by SRB assay, and 1 showed moderate activity against all the tested cell lines with GI50 values ranging from 8.0 to 10.9 µM. -
dc.description.uri 1 -
dc.language English -
dc.publisher Multidisciplinary Digital Publishing Institute (MDPI) -
dc.title New Glycosylated Secondary Metabolites from Marine-Derived Bacteria -
dc.type Article -
dc.citation.title Marine Drugs -
dc.citation.volume 20 -
dc.citation.number 7 -
dc.contributor.alternativeName Cao Van Anh -
dc.contributor.alternativeName 이화선 -
dc.contributor.alternativeName 허창수 -
dc.contributor.alternativeName 신희재 -
dc.identifier.bibliographicCitation Marine Drugs, v.20, no.7 -
dc.identifier.doi 10.3390/md20070464 -
dc.identifier.scopusid 2-s2.0-85135281920 -
dc.identifier.wosid 000832284400001 -
dc.type.docType Article -
dc.description.journalClass 1 -
dc.description.isOpenAccess Y -
dc.subject.keywordAuthor marine-derived bacteria -
dc.subject.keywordAuthor glycosides -
dc.subject.keywordAuthor pityriacitrin -
dc.subject.keywordAuthor trehalose lipid -
dc.subject.keywordAuthor cytotoxicity -
dc.relation.journalWebOfScienceCategory Chemistry, Medicinal -
dc.relation.journalWebOfScienceCategory Pharmacology & Pharmacy -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -
dc.relation.journalResearchArea Pharmacology & Pharmacy -
Appears in Collections:
Marine Resources & Environment Research Division > Marine Biotechnology &Bioresource Research Department > 1. Journal Articles
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