The Synergistic Antibacterial Activity of 1-Acetyl-beta-Carboline and beta-Lactams Against Methicillin-Resistant Staphylococcus aureus (MRSA) SCIE SCOPUS KCI
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Shin, Hee Jae | - |
| dc.contributor.author | Lee, Hyi-Seung | - |
| dc.contributor.author | Lee, Dae-Sung | - |
| dc.date.accessioned | 2020-04-20T08:55:09Z | - |
| dc.date.available | 2020-04-20T08:55:09Z | - |
| dc.date.created | 2020-01-28 | - |
| dc.date.issued | 2010-03 | - |
| dc.identifier.issn | 1017-7825 | - |
| dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/4135 | - |
| dc.description.abstract | 1-Acetyl-beta-carboline was isolated as an anti-MRSA agent from the fermentation broth of a marine actinomycete isolated from marine sediment. The producing strain was identified to be Streptomyces sp. by phylogenetic analysis of the 16S rRNA gene sequence. The anti-MRSA agent was isolated by bioactivity-guided fractionation of the culture extract by solvent partitioning, ODS open flash chromatography, and purification with a reversed-phase HPLC. Its structure was elucidated by extensive 2D NMR and mass spectral analyses. Combination of 1-acetyl-beta-carboline with ampicillin exhibited synergistic antibacterial activity against MRSA. | - |
| dc.description.uri | 1 | - |
| dc.language | English | - |
| dc.publisher | KOREAN SOC MICROBIOLOGY & BIOTECHNOLOGY | - |
| dc.subject | MECHANISMS | - |
| dc.title | The Synergistic Antibacterial Activity of 1-Acetyl-beta-Carboline and beta-Lactams Against Methicillin-Resistant Staphylococcus aureus (MRSA) | - |
| dc.type | Article | - |
| dc.citation.endPage | 505 | - |
| dc.citation.startPage | 501 | - |
| dc.citation.title | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY | - |
| dc.citation.volume | 20 | - |
| dc.citation.number | 3 | - |
| dc.contributor.alternativeName | 신희재 | - |
| dc.contributor.alternativeName | 이희승 | - |
| dc.identifier.bibliographicCitation | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.20, no.3, pp.501 - 505 | - |
| dc.identifier.doi | 10.4014/jmb.0910.10019 | - |
| dc.identifier.scopusid | 2-s2.0-77954292472 | - |
| dc.identifier.wosid | 000276194000008 | - |
| dc.type.docType | Article | - |
| dc.identifier.kciid | ART001430668 | - |
| dc.description.journalClass | 1 | - |
| dc.subject.keywordPlus | MECHANISMS | - |
| dc.subject.keywordAuthor | Streptomyces sp 04DH52 | - |
| dc.subject.keywordAuthor | anti-MRSA agent | - |
| dc.subject.keywordAuthor | 1-acetyl-beta-carboline | - |
| dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
| dc.relation.journalWebOfScienceCategory | Microbiology | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.description.journalRegisteredClass | kci | - |
| dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
| dc.relation.journalResearchArea | Microbiology | - |
- Appears in Collections:
- Marine Resources & Environment Research Division > Marine Biotechnology &Bioresource Research Department > 1. Journal Articles
- Files in This Item:
- There are no files associated with this item.
