Effects of toxic dinoflagellate Alexandrium minutum on the expression of detoxification-related genes in the marine copepod Tigriopus japonicus SCIE SCOPUS

Cited 2 time in WEB OF SCIENCE Cited 2 time in Scopus
Title
Effects of toxic dinoflagellate Alexandrium minutum on the expression of detoxification-related genes in the marine copepod Tigriopus japonicus
Author(s)
Han, Jeonghoon; Park, Joon Sang; Lee, Jihoon; Park, Yeun; Shin, Hyeon Ho; Choi, Young Ung; Lee, Kyun Woo
KIOST Author(s)
null한정훈Park, Joon Sang(박준상)Lee, Ji Hoon(이지훈)Park, Ye Un(박예은)Shin, Hyeon Ho(신현호)Lee, Kyun Woo(이균우)
Alternative Author(s)
한정훈; 박준상; 이지훈; 박예은; 신현호; 최영웅; 이균우
Publication Year
2021-07
Abstract
To understand the effects of the toxic dinoflagellate Alexandrium minutum on the marine copepod Tigriopus japonicus, we assessed acute toxicity and swimming behavior (swimming speed, swimming distance, and swimming path trajectory) in response to A. minutum exposure. No significant changes in survival and swimming behavior were observed in response to A. minutum. Therefore, to validate the effects of A. minutum on the molecular defense response of T. japonicus, we measured mRNA expression levels of detoxification-related genes (phase I cytochrome P450s [CYPs], and phase II glutathione-S transferases [GSTs]) in response to A. minutum. The mRNA expression levels of these detoxification-related genes (CYPs and GSTs) were significantly upregulated and down-regulated (P < 0.05) in response to A. minutum. In particular, CYP3024A2 and GSTTheta3 showed significant up-regulation. Overall, these results suggest that CYP and GST genes are likely to play crucial roles in detoxification mechanisms in T. japonicus, resulting in no significant changes in the survival and swimming behavior of this marine copepod in response to A. minutum exposure.
ISSN
0022-0981
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/41312
DOI
10.1016/j.jembe.2021.151563
Bibliographic Citation
JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY, v.540, 2021
Publisher
ELSEVIER
Subject
HARMFUL ALGAL BLOOMS; GENOME-WIDE IDENTIFICATION; GLUTATHIONE-S-TRANSFERASE; CYTOCHROME-P450 CYP GENES; OXIDATIVE STRESS; SWIMMING BEHAVIOR; CRASSOSTREA-GIGAS; MODULATES EXPRESSION; INTERTIDAL COPEPOD; ANTIOXIDANT SYSTEM
Keywords
Harmful algae bloom; Dinoflagellate; Detoxification; Gene expression; Cytochrome P450s; Glutathione-S transferases
Type
Article
Language
English
Document Type
Article
Publisher
ELSEVIER
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