Growth response to a GH-autotransgenesis in common carp Cyprinus carpio SCOPUS KCI

Title
Growth response to a GH-autotransgenesis in common carp Cyprinus carpio
Author(s)
Noh, C.H.; Kim, D.S.
KIOST Author(s)
Noh, Choong Hwan(노충환)
Publication Year
2012-03
Abstract
Autotransgenic manipulation with a growth hormone (GH)-construct is a potential approach to improving the growth rates of farmed fish. Here, we present the generation of GH-autotransgenic common carp Cyprinus carpio carrying a transgene comprised of the carp homologous GH gene and a β-actin regulator. Autotransgenic carp showed similar viability to their non-transgenic siblings. Early growth characteristics of founder autotransgenic carp up to 50 days postfertilization were highly variable among individuals; i.e., some fish exhibited significant growth depression, while others showed dramatic acceleration of growth, achieving greater than sixfold increases in body weight relative to their non-transgenic counterparts. Stimulated growth performance became more notable with age and many transgenic individuals of the largest class reached 5 kg within 8 or 9 months, which is at least 10 times heavier than the average body weight of communally grown non-transgenics. Four of six founder transgenic males were successful in passing the transgene to their F1 offspring with frequencies ranging from 19 to 36%. Growth stimulations were also persistent in all F1 progeny groups examined. © The Korean Society of Fisheries and Aquatic Science.
ISSN
2234-1749
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/3612
DOI
10.5657/FAS.2012.0037
Bibliographic Citation
Fisheries and Aquatic Sciences, v.15, no.1, pp.37 - 41, 2012
Publisher
한국수산과학회
Keywords
Autotransgenic; Common carp; Cyprinus carpio; Growth enhancement; Growth hormone-transgenesis
Type
Article
Language
English
Document Type
Article
Publisher
한국수산과학회
Related Researcher
Research Interests

Fish genetics and breeding,Living modified organism,Sbtropical mariculture,어류유전육종,어류형질전환,아열대어류양식

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