Growth response to a GH-autotransgenesis in common carp Cyprinus carpio
SCOPUS
KCI
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Title
- Growth response to a GH-autotransgenesis in common carp Cyprinus carpio
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Author(s)
- Noh, C.H.; Kim, D.S.
- KIOST Author(s)
- Noh, Choong Hwan(노충환)
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Alternative Author(s)
- 노충환
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Publication Year
- 2012-03
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Abstract
- Autotransgenic manipulation with a growth hormone (GH)-construct is a potential approach to improving the growth rates of farmed fish. Here, we present the generation of GH-autotransgenic common carp Cyprinus carpio carrying a transgene comprised of the carp homologous GH gene and a β-actin regulator. Autotransgenic carp showed similar viability to their non-transgenic siblings. Early growth characteristics of founder autotransgenic carp up to 50 days postfertilization were highly variable among individuals; i.e., some fish exhibited significant growth depression, while others showed dramatic acceleration of growth, achieving greater than sixfold increases in body weight relative to their non-transgenic counterparts. Stimulated growth performance became more notable with age and many transgenic individuals of the largest class reached 5 kg within 8 or 9 months, which is at least 10 times heavier than the average body weight of communally grown non-transgenics. Four of six founder transgenic males were successful in passing the transgene to their F1 offspring with frequencies ranging from 19 to 36%. Growth stimulations were also persistent in all F1 progeny groups examined. © The Korean Society of Fisheries and Aquatic Science.
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ISSN
- 2234-1749
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URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/3612
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DOI
- 10.5657/FAS.2012.0037
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Bibliographic Citation
- Fisheries and Aquatic Sciences, v.15, no.1, pp.37 - 41, 2012
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Publisher
- 한국수산과학회
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Keywords
- Autotransgenic; Common carp; Cyprinus carpio; Growth enhancement; Growth hormone-transgenesis
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Type
- Article
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Language
- English
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Document Type
- Article
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