Growth response to a GH-autotransgenesis in common carp Cyprinus carpio SCOPUS KCI
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Noh, C.H. | - |
dc.contributor.author | Kim, D.S. | - |
dc.date.accessioned | 2020-04-20T06:55:28Z | - |
dc.date.available | 2020-04-20T06:55:28Z | - |
dc.date.created | 2020-01-28 | - |
dc.date.issued | 2012-03 | - |
dc.identifier.issn | 2234-1749 | - |
dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/3612 | - |
dc.description.abstract | Autotransgenic manipulation with a growth hormone (GH)-construct is a potential approach to improving the growth rates of farmed fish. Here, we present the generation of GH-autotransgenic common carp Cyprinus carpio carrying a transgene comprised of the carp homologous GH gene and a β-actin regulator. Autotransgenic carp showed similar viability to their non-transgenic siblings. Early growth characteristics of founder autotransgenic carp up to 50 days postfertilization were highly variable among individuals; i.e., some fish exhibited significant growth depression, while others showed dramatic acceleration of growth, achieving greater than sixfold increases in body weight relative to their non-transgenic counterparts. Stimulated growth performance became more notable with age and many transgenic individuals of the largest class reached 5 kg within 8 or 9 months, which is at least 10 times heavier than the average body weight of communally grown non-transgenics. Four of six founder transgenic males were successful in passing the transgene to their F1 offspring with frequencies ranging from 19 to 36%. Growth stimulations were also persistent in all F1 progeny groups examined. © The Korean Society of Fisheries and Aquatic Science. | - |
dc.description.uri | 3 | - |
dc.language | English | - |
dc.publisher | 한국수산과학회 | - |
dc.title | Growth response to a GH-autotransgenesis in common carp Cyprinus carpio | - |
dc.type | Article | - |
dc.citation.endPage | 41 | - |
dc.citation.startPage | 37 | - |
dc.citation.title | Fisheries and Aquatic Sciences | - |
dc.citation.volume | 15 | - |
dc.citation.number | 1 | - |
dc.contributor.alternativeName | 노충환 | - |
dc.identifier.bibliographicCitation | Fisheries and Aquatic Sciences, v.15, no.1, pp.37 - 41 | - |
dc.identifier.doi | 10.5657/FAS.2012.0037 | - |
dc.identifier.scopusid | 2-s2.0-84862499178 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001647549 | - |
dc.description.journalClass | 3 | - |
dc.description.isOpenAccess | N | - |
dc.subject.keywordPlus | Cyprinidae | - |
dc.subject.keywordPlus | Cyprinus carpio | - |
dc.subject.keywordAuthor | Autotransgenic | - |
dc.subject.keywordAuthor | Common carp | - |
dc.subject.keywordAuthor | Cyprinus carpio | - |
dc.subject.keywordAuthor | Growth enhancement | - |
dc.subject.keywordAuthor | Growth hormone-transgenesis | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |