New antimicrobial compounds from a marine-derived Bacillus sp. SCIE SCOPUS

Cited 22 time in WEB OF SCIENCE Cited 20 time in Scopus
Title
New antimicrobial compounds from a marine-derived Bacillus sp.
Author(s)
Mondol, Mohamad Abdul Mojid; Tareq, Fakir Shahidullah; Kim, Ji Hye; Lee, Min Ah; Lee, Hyi-Seung; Lee, Jong Seok; Lee, Yeon-Ju; Shin, Hee Jae
KIOST Author(s)
Lee, Min Ah(이민아)Lee, Hyi Seung(이희승)Lee, Jong Seok(이종석)Lee, Yeon Ju(이연주)Shin, Hee Jae(신희재)
Alternative Author(s)
TAREQ; 김지혜; 이민아; 이희승; 이종석; 이연주; 신희재
Publication Year
2013-02
Abstract
In the course of our ongoing research for antimicrobial agents, we isolated five new compounds, three 24-membered macrolactones, macrolactins X-Z (1-3) and two hydroxy unsaturated fatty acids, linieodolides A (5) and B (6), together with a known metabolite, macrolactinic acid (4), from the culture broth of a marine Bacillus sp. The structures of these metabolites were determined on the basis of their spectroscopic data interpretation. Their absolute configurations were addressed by modified Mosher's method and literature data review. Compounds 1-6 showed moderate to potent inhibitory activities (8 similar to 128 mu g ml(-1)) against selected pathogenic microorganisms. The Journal of Antibiotics (2013) 66, 89-95; doi:10.1038/ja.2012.102; published online 5 December 2012
ISSN
0021-8820
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/3274
DOI
10.1038/ja.2012.102
Bibliographic Citation
JOURNAL OF ANTIBIOTICS, v.66, no.2, pp.89 - 95, 2013
Publisher
JAPAN ANTIBIOTICS RESEARCH ASSOC
Subject
ANTIBACTERIAL ACTIVITY; FATTY-ACIDS; MACROLACTINS; LACTONES
Keywords
antimicrobials; linieodolide; macrolactins; marine microorganisms
Type
Article
Language
English
Document Type
Article
Publisher
JAPAN ANTIBIOTICS RESEARCH ASSOC
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