해양 연체동물 Didemnum sp.에서 분리된 2종의 신규 황함유 스테로이드

Title
해양 연체동물 Didemnum sp.에서 분리된 2종의 신규 황함유 스테로이드
Alternative Title
Two New Sulfated Steroids from a Marine Ascidian Didemnum sp.
Author(s)
신희재; 이희승; 박은혜; 신종헌
KIOST Author(s)
Lee, Hyi Seung(이희승)
Publication Year
2004-10-21
Abstract
As part of our program to study on bioactive marine natural products, we have found that extracts of the ascidian Didemnum sp. exhibited cytotoxic activity against human leukemia cell line(K562). Bioassay-guided fractionation of the extracts yielded new polyhydroxylated steroids. We herein report the isolation and structure determination of two new sulfated streroids, 1 and 2. These compounds exhibited cytotoxicity against human leukemia cell line (K-562).
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/31722
Bibliographic Citation
대한약학회 추계 학술발표대회, pp.318, 2004
Publisher
대한약학회
Type
Conference
Language
English
Publisher
대한약학회
Related Researcher
Research Interests

Marine Natural Products,Organic Chemistry,해양천연물,유기화학

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