Oxidative Stress of Nickel on the Embryonic Development of Sea Urchin (Strongylocentrotus intermedius) and Screening of Differentially Expressed Genes Using DD-PCR

Title
Oxidative Stress of Nickel on the Embryonic Development of Sea Urchin (Strongylocentrotus intermedius) and Screening of Differentially Expressed Genes Using DD-PCR
Author(s)
류태권; 박소윤; 황진익; 이택견
KIOST Author(s)
Lee, Taek Kyun(이택견)
Publication Year
2007-11-01
Abstract
Levels of trace metals in seawater ecosystems are altered as a consequence of natural and industrial activities and it can be lead to genotoxicity for marine organisms. Nickel is known for genotoxic agent on the embryonic malformation of the various marine organisms. It is seemmingly important that understanding of how nickel exerts their toxicity and another effect at a molecular and a genomic level. In the preliminary experiments we found that malformation of embryo in the pluteus stage was induced by 72hpf of nickel exposure. In addition, differential display polymerase chain reaction (DD-PCR) technique has been usefully used to hunt the clones which expressions are up-regulated or down-regulated by exterior changes and this study aimed to search for those clones in nickel exposure sea urchin (Strongylocentrotus intermedius) using DD-PCR.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/30252
Bibliographic Citation
ICT-2007 International Conference on Toxicogenomics 2007, pp.59, 2007
Publisher
대한독성유전단백체학회
Type
Conference
Language
English
Publisher
대한독성유전단백체학회
Related Researcher
Research Interests

Marine virus,Marine pathogens,해양바이러스,해양병원체

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