1-Acetyl-ß-carboline compound isolated from a marine actinomycete strain 04DH211

Title
1-Acetyl-ß-carboline compound isolated from a marine actinomycete strain 04DH211
Author(s)
이정수; 유태경; 한종우; Md.Mojid Mondol; 이희승; 신희재
KIOST Author(s)
Lee, Hyi Seung(이희승)
Publication Year
2008-06-26
Abstract
Recently, marine organisms are a recognized source of novel metabolites with valuable biological properties and molecular diversity. Marine organisms have evolved with unique metabolic and physiological capabilities to adapt themselves to extreme habitats. They produce the potent bioactive compounds that would not be observed from terrestrial microorganisms. From the fact that actinomycetes isolated from marine organisms are promising sources for secondary metabolites such as antibiotic substances. Thus, we have focused our exploration on the isolation, structural elucidation of bioactive compounds from marine microorganisms. In the course of our continuing search for new anticancer materials from marine derived actinomycetes, eudistomin class compound was isolated from the culture broth of strain 04DH211. The structure of this compound, which possess significant antibiotic properties, cancer cell cytotoxicities, antifungal, antibacterial in vitro bioassays, was assigned by spectral measurements and comparison with extensive MS, UV and NMR spectral analyses. In this paper we describe the isolation, structure elucidation of this compound.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/29878
Bibliographic Citation
The Korean Society for Microbiology and Biotechnology, pp.322, 2008
Publisher
The Korean Society for Microbiology and Biotechnology
Type
Conference
Language
English
Publisher
The Korean Society for Microbiology and Biotechnology
Related Researcher
Research Interests

Marine Natural Products,Organic Chemistry,해양천연물,유기화학

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