서로다른 추출방법으로 부터 추출된 녹조류의 잠재적 생리활성 평가

Title
서로다른 추출방법으로 부터 추출된 녹조류의 잠재적 생리활성 평가
Alternative Title
Potential bioactivities of marine green algae extracted by different extraction procedure
Author(s)
허수진; You-Jin Jeon; 박흥식; 최영웅; Abu Affan; 이대원; 강도형
KIOST Author(s)
Heo, Soo Jin(허수진)Park, Heung-Sik(박흥식)Lee, Dae Won(이대원)Kang, Do-Hyung(강도형)
Publication Year
2009-03-24
Abstract
This study was conducted to screen potential bioactivities including antioxidant, anti-hypertension, and anticancer activities of methanol and aqueous extracts from 10 marine green algae collected along the coast of Jeju Island in Korea. The extracts were prepared at 20 and 70°C temperature conditions and applied in different bioassays. A variety of extracts evidenced positive effect against reactive oxygen species (ROS), angiotensin converting enzyme (ACE), and various cancer cell lines. Among the algae, Ulva pertusa evidenced prominent inhibitory activity against harmful factors compared with other algae tested in this study, and it is available in large quantities as well as easy to collect. Therefore, U. pertusa was selected for further study. U. pertusa was converted into dried form using different drying methods such as far infrared radiation drying, freeze drying, and okadora drying which were extracted using ethanol and water. Most of the tested extracts evidenced positive effect against ROS whereas the aqueous extract from U. pertusa dried by okadora exhibited higher activity in both 2’,7’-dichlorodihydrofluorescein diacetate (DCFH-DA) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenylte-trazolium bromide (MTT) assays. In addition, U. pertusa was digested by food grade enzymes, and was examined their antioxidant and anticancer activities. The enzymatic digests too evidenced positive effect on both, ROS and anticancer assays. Therefore, these results indicated that green algae could be used as natural source which have potential bioactivities, and further investigations are needed to identify their active components responsible for the potential activities.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/29607
Bibliographic Citation
1st China-Korea (Korea-China) Joint Workshop on Green Tide (Green algal Bloom), pp.287, 2009
Publisher
한국해양연구원
Type
Conference
Language
English
Publisher
한국해양연구원
Related Researcher
Research Interests

Marine ecology,Marine biology,Marine living resources,해양생태,해양생물 생리,해양생물자원

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