Three Tetramic Acid Derivatives, Penicillenols A1, A2, and a New Penicillenol Analog from a Marine Fungus Penicillium citrinum

Title
Three Tetramic Acid Derivatives, Penicillenols A1, A2, and a New Penicillenol Analog from a Marine Fungus Penicillium citrinum
Author(s)
최병규; 이화선; 필감방; 이희승; 이종석; 이연주; 신희재
KIOST Author(s)
Lee, Hwa Sun(이화선)Lee, Hyi Seung(이희승)Lee, Jong Seok(이종석)Lee, Yeon Ju(이연주)Shin, Hee Jae(신희재)
Alternative Author(s)
최병규; 이화선; 필감방; 이희승; 이종석; 이연주; 신희재
Publication Year
2015-04-16
Abstract
Marine organisms have been received significant attention in various fields since they produce unique and novel chemical compounds. Especially, marine microbes are considered as a novel source for biologically and chemically active products. Although marine microbes have been studied to find new and unusual products, lots of microorganisms and their secondary metabolites still remain undiscovered under the ocean. The strain 1310CH-032 was isolated from a sponge collected in Chuuk island, Micronesia and identified as Penicillium citrinum. From this strain, three tetramic acid derivatives, penicillenols A1, A2, and a new penicillenol analog were isolated from the EtOAc extract of the culture broth (25L). The structures of the compounds were determined by using MS and 2D NMR analyses.. Although marine microbes have been studied to find new and unusual products, lots of microorganisms and their secondary metabolites still remain undiscovered under the ocean. The strain 1310CH-032 was isolated from a sponge collected in Chuuk island, Micronesia and identified as Penicillium citrinum. From this strain, three tetramic acid derivatives, penicillenols A1, A2, and a new penicillenol analog were isolated from the EtOAc extract of the culture broth (25L). The structures of the compounds were determined by using MS and 2D NMR analyses.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/25646
Bibliographic Citation
The Korean Society for Biotechnology and Bioengineering, pp.117, 2015
Publisher
The
Type
Conference
Language
English
Publisher
The
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