Thienopyridinone 유도체의 효율적인 합성

DC Field Value Language
dc.contributor.author 박솔 -
dc.contributor.author 설재희 -
dc.contributor.author 이연주 -
dc.contributor.author 이지훈 -
dc.contributor.author 이희승 -
dc.contributor.author 신희재 -
dc.contributor.author 이종석 -
dc.date.accessioned 2020-07-15T23:52:08Z -
dc.date.available 2020-07-15T23:52:08Z -
dc.date.created 2020-02-11 -
dc.date.issued 2015-10-23 -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/25224 -
dc.description.abstract Sulphur- and nitrogen-containing heterocycles are known to have a broad spectrum of biological and pharmacological activities. For these reasons, thieno-pyridinone has been recognized as a important chemical scaffold.In our research program, we found an efficient process for the formation of thienopyridinone and derivaties. This method features using BOP and DIEA as amide coupling reagent. Then it was used for the O-methylation and O-arylation reaction. The synthesis of thienopyridinone is described in this presentation. (1) Amide coupling reaction and cyclization reaction of thiophene. (2) Aromatization reaction of thienopyridinone. (3) O-methylation and O-arylation reaction of thienopyridinone.am, we found an efficient process for the formation of thienopyridinone and derivaties. This method features using BOP and DIEA as amide coupling reagent. Then it was used for the O-methylation and O-arylation reaction. The synthesis of thienopyridinone is described in this presentation. (1) Amide coupling reaction and cyclization reaction of thiophene. (2) Aromatization reaction of thienopyridinone. (3) O-methylation and O-arylation reaction of thienopyridinone. -
dc.description.uri 2 -
dc.language English -
dc.publisher 대한약학회 -
dc.relation.isPartOf 2015 추계국제학술대회 -
dc.title Thienopyridinone 유도체의 효율적인 합성 -
dc.title.alternative Efficient Synthesis of Thienopyridinone Derivatives -
dc.type Conference -
dc.citation.conferencePlace KO -
dc.citation.endPage 83 -
dc.citation.startPage 83 -
dc.citation.title 2015 추계국제학술대회 -
dc.contributor.alternativeName 박솔 -
dc.contributor.alternativeName 설재희 -
dc.contributor.alternativeName 이연주 -
dc.contributor.alternativeName 이지훈 -
dc.contributor.alternativeName 이희승 -
dc.contributor.alternativeName 신희재 -
dc.contributor.alternativeName 이종석 -
dc.identifier.bibliographicCitation 2015 추계국제학술대회, pp.83 -
dc.description.journalClass 2 -
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Marine Resources Research Division > Marine Biotechnology Research Center > 2. Conference Papers
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