Three New Ophiobolins from a Marine Fungus Aspergillus flocculosus

Title
Three New Ophiobolins from a Marine Fungus Aspergillus flocculosus
Author(s)
최병규; 이화선; 이희승; 이종석; 이연주; 이지훈; 신희재
KIOST Author(s)
Lee, Hwa Sun(이화선)Lee, Hyi Seung(이희승)Lee, Jong Seok(이종석)Lee, Yeon Ju(이연주)Lee, Ji Hoon(이지훈)Shin, Hee Jae(신희재)
Alternative Author(s)
최병규; 이화선; 이희승; 이종석; 이연주; 이지훈; 신희재
Publication Year
2018-04-19
Abstract
Secondary metabolites from marine organisms are recognized as a promising source of chemically diverse, structurally novel, and biologically active compounds. Marine microorganisms, particularly marine-derived fungi, have played an important role in discovering pharmaceutical lead compounds. During our ongoing investigation on secondary metabolites from marine microorganisms, the fungus Aspergillus flocculosus 168ST-16.1 was originally isolated from a seaweed Padina sp. collected at Da Nang, Vietnam. Three new ophiobolin derivatives along with ophiobolin C and 6-epi-ophiobolin C were isolated from the crude extract of the strain. The structures of the new compounds were determined by analyses of their MS and NMR spectroscopic data.t role in discovering pharmaceutical lead compounds. During our ongoing investigation on secondary metabolites from marine microorganisms, the fungus Aspergillus flocculosus 168ST-16.1 was originally isolated from a seaweed Padina sp. collected at Da Nang, Vietnam. Three new ophiobolin derivatives along with ophiobolin C and 6-epi-ophiobolin C were isolated from the crude extract of the strain. The structures of the new compounds were determined by analyses of their MS and NMR spectroscopic data.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/23428
Bibliographic Citation
The Korean Society for Biotechnology and Bioengineering, pp.31, 2018
Publisher
The Korean Society for Biotechnology and Bioengineering
Type
Conference
Language
English
Publisher
The Korean Society for Biotechnology and Bioengineering
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