Chemical explorations of the manzamenones from the tropical marine sponge, Plakortis sp

Title
Chemical explorations of the manzamenones from the tropical marine sponge, Plakortis sp
Author(s)
이희승; 이연주; 이종석; 이지훈
KIOST Author(s)
Lee, Hyi Seung(이희승)Lee, Yeon Ju(이연주)Lee, Jong Seok(이종석)Lee, Jihoon(이지훈)
Publication Year
2019-08-27
Abstract
A new manzamenone derivative and four known manzamenones were isolated from the tropical marine sponge Plakortis sp. These compounds exhibited an improved inhibitory effect against the copper-induced LDL oxidation. Among these known compounds, 43-O-methylmanzamenone A has been exposed oxidative conditions such as hydrogen peroxide, mCPBA and primary alkyl amines to give various derivatives. Their structures were elucidated on the basis of mass spectrometry and detailed 2D NMR spectroscopic data.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/22416
Bibliographic Citation
American Chemical Society 2019 Fall National Meeting, pp.1, 2019
Publisher
미국화학회
Type
Conference
Language
English
Publisher
미국화학회
Related Researcher
Research Interests

Marine Natural Products,Organic Chemistry,해양천연물,유기화학

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