심해 퇴적물에서 분리된 곰팡이 Cystobasidium laryngis 유래의 항염 물질

Title
심해 퇴적물에서 분리된 곰팡이 Cystobasidium laryngis 유래의 항염 물질
Alternative Title
Anti-Inflammatory Metabolites from the Deep-Sea Sediment-Derived Fungus Cystobasidium laryngis
Author(s)
이화선; 강종순; 최병규; 신희재
KIOST Author(s)
Lee, Hwa Sun(이화선)Choi, Byeoung Kyu(최병규)
Publication Year
2019-10-11
Abstract
Marine microorganisms are recognized as an important source for drug discovery because they produce secondary metabolites with different skeleton and diverse bioactivities than terrestrial counterparts [1, 2]. Especially, marine microbes derived from the deep-sea are relatively untapped reservoir of metabolites with structural and biological diversity waiting to be discovered because of lack of technology and the difficulty of collecting samples [3]. In our continuing research for bioactive substances from deep-sea microorganisms, we encountered a marine-derived yeast-like fungus Cystobasidium laryngis isolated from a deep-sea sediment sample. Here, we report the fermentation, isolation, structure elucidation and anti-inflammatory activities of three new and four known phenazine derivatives produced by the deep-sea derived fungus C. laryngis.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/22256
Bibliographic Citation
2019 한국생물공학회 추계학술발표대회, pp.1, 2019
Publisher
한국생물공학회
Type
Conference
Language
English
Publisher
한국생물공학회
Related Researcher
Research Interests

Marine natural product,Marine microorganisms,해양천연물,해양미생물

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