Differential Toxicokinetics Determines the Sensitivity of Two Marine Embryonic Fish Exposed to Iranian Heavy Crude Oil SCIE SCOPUS

Cited 41 time in WEB OF SCIENCE Cited 46 time in Scopus
Title
Differential Toxicokinetics Determines the Sensitivity of Two Marine Embryonic Fish Exposed to Iranian Heavy Crude Oil
Author(s)
Jung, Jee-Hyun; Kim, Moonkoo; Yim, Un Hyuk; Ha, Sung Yong; Shim, Won Joon; Chae, Young Sun; Kim, Hana; Incardona, John P.; Linbo, Tiffany L.; Kwon, Jung-Hwan
KIOST Author(s)
Jung, Jee Hyun(정지현)Kim, Moon Koo(김문구)Yim, Un Hyuk(임운혁)Ha, Sung Yong(하성용)Shim, Won Joon(심원준)
Publication Year
2015-11-17
Abstract
Interspecific difference in the developmental toxicity of crude oil to embryonic fish allows the prediction of injury extent to a number of resident fish species in oil spill sites. This study clarifies the comparative developmental effects of Iranian heavy crude oil (IHCO) on the differences of biouptake and toxic sensitivity between embryonic spotted sea bass (Lateolabrax maculates) and olive flounder (Paralichthys olivaceus). From 24 h after exposure to IHCO, several morphological defects were observed in both species of embryonic fish, including pericardial edema, dorsal curvature of the trunk, developmental delay, and reduced finfolds. The severity of defects was greater in flounder compared to that in sea bass. While flounder embryos accumulated higher embryo PAH concentrations than sea bass, the former showed significantly lower levels of CYP1A expression. Although bioconcentration ratios were similar between the two species for some PAHs, phenanthrenes and dibenzothiophenes showed selectively higher bioconcentration ratios in flounder, suggesting that this species has a reduced metabolic capacity for these compounds. While consistent with a conserved cardiotoxic mechanism for petrogenic PAHs across diverse marine and freshwater species, these findings indicate that species-specific differences in toxicokinetics can be an important factor underlying species' sensitivity to crude oil.
ISSN
0013-936X
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/2089
DOI
10.1021/acs.est.5b03729
Bibliographic Citation
ENVIRONMENTAL SCIENCE & TECHNOLOGY, v.49, no.22, pp.13639 - 13648, 2015
Publisher
AMER CHEMICAL SOC
Subject
POLYCYCLIC AROMATIC-HYDROCARBONS; SALMON ONCORHYNCHUS-GORBUSCHA; HERRING CLUPEA-PALLASI; EARLY-LIFE STAGES; EXXON-VALDEZ; DEVELOPMENTAL TOXICITY; ZEBRAFISH; KOREA; SPILL; MORTALITY
Type
Article
Language
English
Document Type
Article
Publisher
AMER CHEMICAL SOC
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