Differential Toxicokinetics Determines the Sensitivity of Two Marine Embryonic Fish Exposed to Iranian Heavy Crude Oil SCIE SCOPUS

DC Field Value Language
dc.contributor.author Jung, Jee-Hyun -
dc.contributor.author Kim, Moonkoo -
dc.contributor.author Yim, Un Hyuk -
dc.contributor.author Ha, Sung Yong -
dc.contributor.author Shim, Won Joon -
dc.contributor.author Chae, Young Sun -
dc.contributor.author Kim, Hana -
dc.contributor.author Incardona, John P. -
dc.contributor.author Linbo, Tiffany L. -
dc.contributor.author Kwon, Jung-Hwan -
dc.date.accessioned 2020-04-20T02:05:16Z -
dc.date.available 2020-04-20T02:05:16Z -
dc.date.created 2020-02-18 -
dc.date.issued 2015-11-17 -
dc.identifier.issn 0013-936X -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/2089 -
dc.description.abstract Interspecific difference in the developmental toxicity of crude oil to embryonic fish allows the prediction of injury extent to a number of resident fish species in oil spill sites. This study clarifies the comparative developmental effects of Iranian heavy crude oil (IHCO) on the differences of biouptake and toxic sensitivity between embryonic spotted sea bass (Lateolabrax maculates) and olive flounder (Paralichthys olivaceus). From 24 h after exposure to IHCO, several morphological defects were observed in both species of embryonic fish, including pericardial edema, dorsal curvature of the trunk, developmental delay, and reduced finfolds. The severity of defects was greater in flounder compared to that in sea bass. While flounder embryos accumulated higher embryo PAH concentrations than sea bass, the former showed significantly lower levels of CYP1A expression. Although bioconcentration ratios were similar between the two species for some PAHs, phenanthrenes and dibenzothiophenes showed selectively higher bioconcentration ratios in flounder, suggesting that this species has a reduced metabolic capacity for these compounds. While consistent with a conserved cardiotoxic mechanism for petrogenic PAHs across diverse marine and freshwater species, these findings indicate that species-specific differences in toxicokinetics can be an important factor underlying species' sensitivity to crude oil. -
dc.description.uri 1 -
dc.language English -
dc.publisher AMER CHEMICAL SOC -
dc.subject POLYCYCLIC AROMATIC-HYDROCARBONS -
dc.subject SALMON ONCORHYNCHUS-GORBUSCHA -
dc.subject HERRING CLUPEA-PALLASI -
dc.subject EARLY-LIFE STAGES -
dc.subject EXXON-VALDEZ -
dc.subject DEVELOPMENTAL TOXICITY -
dc.subject ZEBRAFISH -
dc.subject KOREA -
dc.subject SPILL -
dc.subject MORTALITY -
dc.title Differential Toxicokinetics Determines the Sensitivity of Two Marine Embryonic Fish Exposed to Iranian Heavy Crude Oil -
dc.type Article -
dc.citation.endPage 13648 -
dc.citation.startPage 13639 -
dc.citation.title ENVIRONMENTAL SCIENCE & TECHNOLOGY -
dc.citation.volume 49 -
dc.citation.number 22 -
dc.identifier.bibliographicCitation ENVIRONMENTAL SCIENCE & TECHNOLOGY, v.49, no.22, pp.13639 - 13648 -
dc.identifier.doi 10.1021/acs.est.5b03729 -
dc.identifier.scopusid 2-s2.0-84947252118 -
dc.identifier.wosid 000365151200063 -
dc.type.docType Article -
dc.description.journalClass 1 -
dc.subject.keywordPlus POLYCYCLIC AROMATIC-HYDROCARBONS -
dc.subject.keywordPlus SALMON ONCORHYNCHUS-GORBUSCHA -
dc.subject.keywordPlus HERRING CLUPEA-PALLASI -
dc.subject.keywordPlus EARLY-LIFE STAGES -
dc.subject.keywordPlus EXXON-VALDEZ -
dc.subject.keywordPlus DEVELOPMENTAL TOXICITY -
dc.subject.keywordPlus ZEBRAFISH -
dc.subject.keywordPlus KOREA -
dc.subject.keywordPlus SPILL -
dc.subject.keywordPlus MORTALITY -
dc.relation.journalWebOfScienceCategory Engineering, Environmental -
dc.relation.journalWebOfScienceCategory Environmental Sciences -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -
dc.relation.journalResearchArea Engineering -
dc.relation.journalResearchArea Environmental Sciences & Ecology -
Appears in Collections:
South Sea Research Institute > Risk Assessment Research Center > 1. Journal Articles
Files in This Item:
There are no files associated with this item.

qrcode

Items in ScienceWatch@KIOST are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse