CETP inhibitory activity of ceramides, isolated from the gorgonian Acabaria undulata
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Title
- CETP inhibitory activity of ceramides, isolated from the gorgonian Acabaria undulata
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Author(s)
- Jeong, TS; Ahn, JA; Kim, YK; Bok, SH; Kwon, BM; Shin, J; Seo, Y
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Alternative Author(s)
- 신종헌; 서영완
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Publication Year
- 1997-06-03
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Abstract
- Four ceramides, isolated from the gorgonian Acabaria Undulata, and sphingosine analogs exhibited significant cholesteryl ester transfer protein (CETP)inhibitory activity. The ceramides 1, 2, 3, 4 and N,N-dimethylsphingosine inhibited human CETP with IC50 values of 46.8, 57.3, 86.3, 65.6 and 6.3 mu M, respectively. (C) 1997 Elsevier Science Ltd.
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ISSN
- 0960-894X
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URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/6369
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DOI
- 10.1016/S0960-894X(97)00248-5
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Bibliographic Citation
- BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.7, no.11, pp.1481 - 1482, 1997
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Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
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Subject
- ESTER TRANSFER PROTEIN; CHOLESTERYL
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Type
- Article
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Language
- English
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Document Type
- Article
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Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
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