Topoisomerase I inhibitors from the Streptomyces sp. strain KM86-9B isolated from a marine sponge SCIE SCOPUS

Cited 21 time in WEB OF SCIENCE Cited 28 time in Scopus
Title
Topoisomerase I inhibitors from the Streptomyces sp. strain KM86-9B isolated from a marine sponge
Author(s)
Lee, HK; Lee, DS; Lim, J; Kim, JS; Im, KS; Jung, JH
Publication Year
1998-12
Abstract
The crude extract of Streptomyces sp. strain KM86-9B, isolated from a marine sponge, displayed significant inhibition on topoisomerase I activity. investigation of the causative components by bioactivity-directed fractionation resulted in the isolation of a series of iso- and anteiso-fatty acids.
ISSN
0253-6269
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/6242
DOI
10.1007/BF02976766
Bibliographic Citation
ARCHIVES OF PHARMACAL RESEARCH, v.21, no.6, pp.729 - 733, 1998
Publisher
PHARMACEUTICAL SOCIETY KOREA
Subject
DNA TOPOISOMERASES; PHOSPHOLIPIDS; CAMPTOTHECIN; FAGARONINE; BINDING; AGENT
Keywords
topoisomerase I inhibitor; marine actinomycete; iso-fatty acids; anteiso-fatty acids; marine sponge
Type
Article
Language
English
Document Type
Article
Publisher
PHARMACEUTICAL SOCIETY KOREA
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