Topoisomerase I inhibitors from the Streptomyces sp. strain KM86-9B isolated from a marine sponge SCIE SCOPUS
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- Title
- Topoisomerase I inhibitors from the Streptomyces sp. strain KM86-9B isolated from a marine sponge
- Alternative Author(s)
- 이득수; 정지형
- Publication Year
- 1998-12
- Abstract
- The crude extract of Streptomyces sp. strain KM86-9B, isolated from a marine sponge, displayed significant inhibition on topoisomerase I activity. investigation of the causative components by bioactivity-directed fractionation resulted in the isolation of a series of iso- and anteiso-fatty acids.
- ISSN
- 0253-6269
- Bibliographic Citation
- ARCHIVES OF PHARMACAL RESEARCH, v.21, no.6, pp.729 - 733, 1998
- Publisher
- PHARMACEUTICAL SOCIETY KOREA
- Subject
- DNA TOPOISOMERASES; PHOSPHOLIPIDS; CAMPTOTHECIN; FAGARONINE; BINDING; AGENT
- Keywords
- topoisomerase I inhibitor; marine actinomycete; iso-fatty acids; anteiso-fatty acids; marine sponge
- Type
- Article
- Language
- English
- Document Type
- Article
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