Euplexides A-E: Novel farnesylhydroquinone glycosides from the gorgonian Euplexaura anastomosans

Abstract

Euplexides A-E (1-5), novel farnesylhydroquinone glycosides of the moritoside class, have been isolated from the gorgonian Euplexaura anastomosans. The structures of these compounds have been elucidated by combined chemical and spectral methods. The absolute stereochemistry has been determined by the modified Mosher's method and an acidic hydrolysis followed by GC analysis. These compounds exhibited moderate cytotoxicity and antioxidizing activity as well as inhibitory activity against PLA(2).