Cytotoxic polyacetylenes from the marine sponge Petrosia sp.
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Title
- Cytotoxic polyacetylenes from the marine sponge Petrosia sp.
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Author(s)
- Kim, JS; Lim, YJ; Im, KS; Jung, JH; Shim, CJ; Lee, CO; Hong, J; Lee, H
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Alternative Author(s)
- 이홍금
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Publication Year
- 1999-04
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Abstract
- Three C-46 (1--3) and three C-30 (4-6) polyacetylenic alcohols with cytotoxic activity against a small panel of human solid-tumor cell lines have been isolated from the marine sponge Petrosia sp. Although compound 1 was identified as the stereoisomer of petrocortyne A, the structures of compounds 2-5 have not been previously reported and were established by spectral methods. Compound 6 was identified as the known compound petrosiacetylene D. The stereochemistry of compounds 1-5 was determined by the modified Mosher's method.
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ISSN
- 0163-3864
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URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/6169
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DOI
- 10.1021/np9803427
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Bibliographic Citation
- JOURNAL OF NATURAL PRODUCTS, v.62, no.4, pp.554 - 559, 1999
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Publisher
- AMER CHEMICAL SOC
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Subject
- MOLECULAR-WEIGHT POLYACETYLENES; BIOACTIVE POLYACETYLENES; ABSOLUTE-CONFIGURATION; CRIBROCHALINA-VASCULUM; ACETYLENIC ALCOHOLS; GENUS PETROSIA; FICIFORMIS; PETROFORMYNES; METABOLITES; INHIBITORS
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Type
- Article
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Language
- English
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Document Type
- Article
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