Cytotoxic polyacetylenes from the marine sponge Petrosia sp. SCIE SCOPUS

Cited 56 time in WEB OF SCIENCE Cited 0 time in Scopus
Title
Cytotoxic polyacetylenes from the marine sponge Petrosia sp.
Author(s)
Kim, JS; Lim, YJ; Im, KS; Jung, JH; Shim, CJ; Lee, CO; Hong, J; Lee, H
Publication Year
1999-04
Abstract
Three C-46 (1--3) and three C-30 (4-6) polyacetylenic alcohols with cytotoxic activity against a small panel of human solid-tumor cell lines have been isolated from the marine sponge Petrosia sp. Although compound 1 was identified as the stereoisomer of petrocortyne A, the structures of compounds 2-5 have not been previously reported and were established by spectral methods. Compound 6 was identified as the known compound petrosiacetylene D. The stereochemistry of compounds 1-5 was determined by the modified Mosher's method.
ISSN
0163-3864
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/6169
DOI
10.1021/np9803427
Bibliographic Citation
JOURNAL OF NATURAL PRODUCTS, v.62, no.4, pp.554 - 559, 1999
Publisher
AMER CHEMICAL SOC
Subject
MOLECULAR-WEIGHT POLYACETYLENES; BIOACTIVE POLYACETYLENES; ABSOLUTE-CONFIGURATION; CRIBROCHALINA-VASCULUM; ACETYLENIC ALCOHOLS; GENUS PETROSIA; FICIFORMIS; PETROFORMYNES; METABOLITES; INHIBITORS
Type
Article
Language
English
Document Type
Article
Publisher
AMER CHEMICAL SOC
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