Synthesis and characterization of a ferric complex of the tripodal ligand tris(2-benzimidazolylmethyl)amine - a superoxide dismutase mimic SCIE SCOPUS

Cited 21 time in WEB OF SCIENCE Cited 20 time in Scopus
Title
Synthesis and characterization of a ferric complex of the tripodal ligand tris(2-benzimidazolylmethyl)amine - a superoxide dismutase mimic
Author(s)
Kwak, B; Cho, KW; Pyo, M; Lah, MS
Publication Year
1999-06-30
Abstract
The mononuclear iron complex 1 was synthesized using a tripedal ligand, tris(2-benzimidazolylmethyl) amine (ntb), where ntb served as a neutral tetradentate chelating ligand for the distorted octahedral ferric ion. Three benzimidazole groups of ntb and one chloride anion formed a base of octahedral geometry. One of the two axial positions was occupied by an apical nitrogen atom of ntb and the other site was occupied by another chloride anion. Two of the chloride anions in complex 1 are in a cis arrangement. The decay of the electrochemically generated superoxide radical (O-2(-)) by complex 1 was observed using cyclic voltammetry. The superoxide dismutase (SOD) activity of complex 1 was also examined using a modified method of the light- and riboflavin-driven hydroxylaminenitrate assay. Reaction of complex 1 with an O-2(-) radical in methanol gave the mu-oxo dinuclear iron complex 2. The mu-oxo group was substituted for the basal chloride anion of complex 1 in complex 2. Complex 2 could also be synthesized using weak bases instead of the O-2(-) radical. (C) 1999 Elsevier Science S.A. All rights reserved.
ISSN
0020-1693
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/6159
DOI
10.1016/S0020-1693(99)00091-2
Bibliographic Citation
INORGANICA CHIMICA ACTA, v.290, no.1, pp.21 - 27, 1999
Publisher
ELSEVIER SCIENCE SA
Subject
MANGANESE(II) COMPLEX; CRYSTAL-STRUCTURE; ZINC-COMPLEXES; TRIS(IMIDAZOLYLMETHYL)AMINE LIGANDS; IRON CENTERS; 5-COORDINATE; 6-COORDINATE; REACTIVITY; MODEL; COBALT(II)
Keywords
iron complexes; tripodal amine complexes; superoxide radical; superoxide dismutase
Type
Article
Language
English
Document Type
Article
Publisher
ELSEVIER SCIENCE SA
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