New polyene macrolide antibiotics from Streptomyces sp M90025
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Title
- New polyene macrolide antibiotics from Streptomyces sp M90025
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Author(s)
- Seo, Y; Cho, KW; Lee, HS; Yoon, TM; Shin, JH
- KIOST Author(s)
- Lee, Hyi Seung(이희승)
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Alternative Author(s)
- 서영완; 조기웅; 이희승; 윤태미; 신종헌
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Publication Year
- 2000-04
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Abstract
- Three polyene macrolide antibiotics including two new compounds were isolated from the culture mycelia of a Streptomyces species. The structures of these metabolites were determined as elizabethin, a previously reported 28-membered macrolide and two analogs, using combined spectroscopic methods. These compounds exhibited antifungal activity and cytotoxicity against a human leukemia cell.
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ISSN
- 1017-7825
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URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/6071
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Bibliographic Citation
- JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.10, no.2, pp.176 - 180, 2000
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Publisher
- SPRINGER-VERLAG SINGAPORE PTE LTD
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Subject
- ASSIGNMENT
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Keywords
- polyene antibiotics; 28-membered macrolides; Streptomyces; elizabethin
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Type
- Article
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Language
- English
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Document Type
- Article
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