Wondonins A and B, new bis(dihydroxystyryl)imidazoles from a two-sponge association
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Title
- Wondonins A and B, new bis(dihydroxystyryl)imidazoles from a two-sponge association
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Author(s)
- Shin, J; Rho, JR; Seo, Y; Lee, HS; Cho, KW; Kwon, HJ; Sim, CJ
- KIOST Author(s)
- Lee, Hyi Seung(이희승)
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Alternative Author(s)
- 신종헌; 노정래; 이희승; 조기웅
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Publication Year
- 2001-03-04
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Abstract
- Wondonins A and B, two alkaloids of an unprecedented structural class, along with the previously described dihydroxystyryl sulfates, have been isolated from an association of the sponges Poecillastra wondoensis and Jaspis sp. collected from Keomun Island, Korea. The structures of these compounds have been determined as imidazole alkaloids containing a bis(dihydroxystyrene) moiety by combined spectroscopic methods. The new compounds exhibited antiangiogenic activity against human umbilical vein endothelial cells. (C) 2001 Elsevier Science Ltd. All rights reserved.
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ISSN
- 0040-4039
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URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/5905
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DOI
- 10.1016/S0040-4039(01)00092-2
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Bibliographic Citation
- TETRAHEDRON LETTERS, v.42, no.10, pp.1965 - 1968, 2001
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Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
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Subject
- MARINE SPONGE; JASPIS SP; STYRYL SULFATE; METAMORPHOSIS; INDUCERS
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Keywords
- marine metabolites; Poecillastra wondoensis; Jaspis sp.; imidazole alkaloids
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Type
- Article
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Language
- English
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Document Type
- Article
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