Hydrazinocurcumin, a novel synthetic curcumin derivative, is a potent inhibitor of endothelial cell proliferation SCIE SCOPUS

DC Field Value Language
dc.contributor.author Shim, JS -
dc.contributor.author Kim, DH -
dc.contributor.author Jung, HJ -
dc.contributor.author Kim, JH -
dc.contributor.author Lim, D -
dc.contributor.author Lee, SK -
dc.contributor.author Kim, KW -
dc.contributor.author Ahn, JW -
dc.contributor.author Yoo, JS -
dc.contributor.author Rho, JR -
dc.contributor.author Shin, J -
dc.contributor.author Kwon, HJ -
dc.date.accessioned 2020-04-21T06:55:31Z -
dc.date.available 2020-04-21T06:55:31Z -
dc.date.created 2020-01-28 -
dc.date.issued 2002-09 -
dc.identifier.issn 0968-0896 -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/5670 -
dc.description.abstract Curcumin and some of its derivatives were known as in vivo inhibitors of angiogenesis. In present study. a novel curcumin derivative, named hydrazinocurcumin (HC) was synthesized and examined for its biological activities. HC potently inhibited the proliferation of bovine aortic endothelial cells (BAECs) at a nanomolar concentration (IC50 = 520 nM) without cytotoxicity. In vivo and in Nitro angiogenesis experiments showed HC Lis a new candidate for anti-angiogenic agent. (C) 2002 Published by Elsevier Science Ltd. -
dc.description.uri 1 -
dc.language English -
dc.publisher PERGAMON-ELSEVIER SCIENCE LTD -
dc.subject COLON CARCINOGENESIS -
dc.subject DIETARY CURCUMIN -
dc.subject TUMOR PROMOTION -
dc.subject ANGIOGENESIS -
dc.subject ANALOGS -
dc.subject TETRAHYDROCURCUMIN -
dc.subject MECHANISMS -
dc.subject GROWTH -
dc.title Hydrazinocurcumin, a novel synthetic curcumin derivative, is a potent inhibitor of endothelial cell proliferation -
dc.type Article -
dc.citation.endPage 2992 -
dc.citation.startPage 2987 -
dc.citation.title BIOORGANIC & MEDICINAL CHEMISTRY -
dc.citation.volume 10 -
dc.citation.number 9 -
dc.identifier.bibliographicCitation BIOORGANIC & MEDICINAL CHEMISTRY, v.10, no.9, pp.2987 - 2992 -
dc.identifier.doi 10.1016/S0968-0896(02)00129-3 -
dc.identifier.scopusid 2-s2.0-19044373252 -
dc.identifier.wosid 000177484800020 -
dc.type.docType Article -
dc.description.journalClass 1 -
dc.subject.keywordPlus COLON CARCINOGENESIS -
dc.subject.keywordPlus DIETARY CURCUMIN -
dc.subject.keywordPlus TUMOR PROMOTION -
dc.subject.keywordPlus ANGIOGENESIS -
dc.subject.keywordPlus ANALOGS -
dc.subject.keywordPlus TETRAHYDROCURCUMIN -
dc.subject.keywordPlus MECHANISMS -
dc.subject.keywordPlus GROWTH -
dc.relation.journalWebOfScienceCategory Biochemistry & Molecular Biology -
dc.relation.journalWebOfScienceCategory Chemistry, Medicinal -
dc.relation.journalWebOfScienceCategory Chemistry, Organic -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -
dc.relation.journalResearchArea Biochemistry & Molecular Biology -
dc.relation.journalResearchArea Pharmacology & Pharmacy -
dc.relation.journalResearchArea Chemistry -
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