Hydrazinocurcumin, a novel synthetic curcumin derivative, is a potent inhibitor of endothelial cell proliferation SCIE SCOPUS
DC Field | Value | Language |
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dc.contributor.author | Shim, JS | - |
dc.contributor.author | Kim, DH | - |
dc.contributor.author | Jung, HJ | - |
dc.contributor.author | Kim, JH | - |
dc.contributor.author | Lim, D | - |
dc.contributor.author | Lee, SK | - |
dc.contributor.author | Kim, KW | - |
dc.contributor.author | Ahn, JW | - |
dc.contributor.author | Yoo, JS | - |
dc.contributor.author | Rho, JR | - |
dc.contributor.author | Shin, J | - |
dc.contributor.author | Kwon, HJ | - |
dc.date.accessioned | 2020-04-21T06:55:31Z | - |
dc.date.available | 2020-04-21T06:55:31Z | - |
dc.date.created | 2020-01-28 | - |
dc.date.issued | 2002-09 | - |
dc.identifier.issn | 0968-0896 | - |
dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/5670 | - |
dc.description.abstract | Curcumin and some of its derivatives were known as in vivo inhibitors of angiogenesis. In present study. a novel curcumin derivative, named hydrazinocurcumin (HC) was synthesized and examined for its biological activities. HC potently inhibited the proliferation of bovine aortic endothelial cells (BAECs) at a nanomolar concentration (IC50 = 520 nM) without cytotoxicity. In vivo and in Nitro angiogenesis experiments showed HC Lis a new candidate for anti-angiogenic agent. (C) 2002 Published by Elsevier Science Ltd. | - |
dc.description.uri | 1 | - |
dc.language | English | - |
dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
dc.subject | COLON CARCINOGENESIS | - |
dc.subject | DIETARY CURCUMIN | - |
dc.subject | TUMOR PROMOTION | - |
dc.subject | ANGIOGENESIS | - |
dc.subject | ANALOGS | - |
dc.subject | TETRAHYDROCURCUMIN | - |
dc.subject | MECHANISMS | - |
dc.subject | GROWTH | - |
dc.title | Hydrazinocurcumin, a novel synthetic curcumin derivative, is a potent inhibitor of endothelial cell proliferation | - |
dc.type | Article | - |
dc.citation.endPage | 2992 | - |
dc.citation.startPage | 2987 | - |
dc.citation.title | BIOORGANIC & MEDICINAL CHEMISTRY | - |
dc.citation.volume | 10 | - |
dc.citation.number | 9 | - |
dc.contributor.alternativeName | 노정래 | - |
dc.identifier.bibliographicCitation | BIOORGANIC & MEDICINAL CHEMISTRY, v.10, no.9, pp.2987 - 2992 | - |
dc.identifier.doi | 10.1016/S0968-0896(02)00129-3 | - |
dc.identifier.scopusid | 2-s2.0-19044373252 | - |
dc.identifier.wosid | 000177484800020 | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | COLON CARCINOGENESIS | - |
dc.subject.keywordPlus | DIETARY CURCUMIN | - |
dc.subject.keywordPlus | TUMOR PROMOTION | - |
dc.subject.keywordPlus | ANGIOGENESIS | - |
dc.subject.keywordPlus | ANALOGS | - |
dc.subject.keywordPlus | TETRAHYDROCURCUMIN | - |
dc.subject.keywordPlus | MECHANISMS | - |
dc.subject.keywordPlus | GROWTH | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalResearchArea | Chemistry | - |