New macrolides from the sponge Chondrosia corticata
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Title
- New macrolides from the sponge Chondrosia corticata
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Author(s)
- Shin, J; Lee, HS; Kim, JY; Shin, HJ; Ahn, JW; Paul, VJ
- KIOST Author(s)
- Lee, Hyi Seung(이희승); Shin, Hee Jae(신희재)
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Alternative Author(s)
- 이희승; 신희재
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Publication Year
- 2004-11
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Abstract
- Three new oxazole-containing metabolites, neohalichondramide (5), (19Z)-halichondramide (6), and secohalichondramide (7), along with four previously reported compounds of the same structural class were isolated from the marine sponge Chondrosia corticata collected from Guam. The structures of novel compounds were determined on the basis of combined spectroscopic analyses. These compounds exhibited significant cytotoxicity and antifungal activity toward the human leukemia cell-line K562 and Candida albicans, respectively.
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ISSN
- 0163-3864
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URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/5201
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DOI
- 10.1021/np040124f
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Bibliographic Citation
- JOURNAL OF NATURAL PRODUCTS, v.67, no.11, pp.1889 - 1892, 2004
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Publisher
- AMER CHEMICAL SOC
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Subject
- NUDIBRANCH HEXABRANCHUS-SANGUINEUS; MARINE SPONGE; CYTOTOXIC MACROLIDES; MYCALE-MAGELLANICA; METABOLITES; MYCALOLIDES; HALICHONDRIA; ULAPUALIDE; EGGMASSES; OXAZOLE
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Type
- Article
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Language
- English
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Document Type
- Article
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