Comet assay를 이용한 갯지렁이 (Perinereis aibuhitensis)의 혈구세포에 대한 유전독성 평가 KCI OTHER

Title
Comet assay를 이용한 갯지렁이 (Perinereis aibuhitensis)의 혈구세포에 대한 유전독성 평가
Alternative Title
Evaluation of Genotoxicity in Blood Cells of a Polychaetous Worm (Perinereis aibuhitensis),Using Comet Assay
Author(s)
서진영; 성찬경; 최진우; 이창훈; 류태권; 한기명; 김기범
Publication Year
2005-12
Abstract
In order to know whether polychaetes could be used as an appropriate organism for the detection ofgenotoxicity, DNA strand breaks were evaluated in blood cells of a nereidae worm (Perinereis aibuhitensis)exposed to various aquatic chemical pollutants (e.g. Cd, Pb, Pyrene, Benzo[a]pyrene). Hydrogen peroxideincreased DNA strand breaks up to the highest concentration (10M). Higher concentration than 0.1Mshowed a significantly more DNA damage than control. Cadmium and lead also showed higher DNA damagethan control, over 1.0 and 1g/L, respectively. In case of pyrene, DNA damage was detected even at 0.001study suggested that the polychaetous blood cells could be used effectively for screening genotoxic contami-nants in the environment.
ISSN
2093-6400
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/4990
Bibliographic Citation
환경독성보건학회지, v.20, no.4, pp.333 - 341, 2005
Publisher
환경독성보건학회
Keywords
comet assay; polychaetous blood cell; bioassay; metal; PAH
Type
Article
Language
Korean
Publisher
환경독성보건학회
Files in This Item:
There are no files associated with this item.

qrcode

Items in ScienceWatch@KIOST are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse