Isolation and structure determination of streptochlorin, an antiproliferative agent from a marine-derived Streptomyces sp 04DH110 SCIE SCOPUS KCI
DC Field | Value | Language |
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dc.contributor.author | Shin, Hee Jae | - |
dc.contributor.author | Jeong, Hyun Sun | - |
dc.contributor.author | Lee, Hyi-Seung | - |
dc.contributor.author | Park, Song-Kyu | - |
dc.contributor.author | Kim, Hwan Mook | - |
dc.contributor.author | Kwon, Ho Jeong | - |
dc.date.accessioned | 2020-04-20T11:55:13Z | - |
dc.date.available | 2020-04-20T11:55:13Z | - |
dc.date.created | 2020-01-28 | - |
dc.date.issued | 2007-08 | - |
dc.identifier.issn | 1017-7825 | - |
dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/4669 | - |
dc.description.abstract | An antiproliferative agent, streptochlorin, was isolated from the fermentation broth of a marine actinomycete isolated from marine sediment. Phylogenetic analysis of the 16S rRNA gene sequence indicated that the strain belongs to the genus Streptomyces. Bioactivity guided fractionation of the culture extract by solvent partitioning, ODS open flash chromatography, and reversed-phase HPLC gave a pure compound, streptochlorin. Its structure was elucidated by extensive 2D NMR and mass spectral analyses. Streptochlorin exhibited significant antiproliferative activity against human cultured cell lines. | - |
dc.description.uri | 1 | - |
dc.language | English | - |
dc.publisher | KOREAN SOC MICROBIOLOGY & BIOTECHNOLOGY | - |
dc.subject | BACTERIUM | - |
dc.subject | DERIVATIVES | - |
dc.title | Isolation and structure determination of streptochlorin, an antiproliferative agent from a marine-derived Streptomyces sp 04DH110 | - |
dc.type | Article | - |
dc.citation.endPage | 1406 | - |
dc.citation.startPage | 1403 | - |
dc.citation.title | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY | - |
dc.citation.volume | 17 | - |
dc.citation.number | 8 | - |
dc.contributor.alternativeName | 신희재 | - |
dc.contributor.alternativeName | 이희승 | - |
dc.identifier.bibliographicCitation | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.17, no.8, pp.1403 - 1406 | - |
dc.identifier.scopusid | 2-s2.0-34548510609 | - |
dc.identifier.wosid | 000249111700025 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001184808 | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | BACTERIUM | - |
dc.subject.keywordPlus | DERIVATIVES | - |
dc.subject.keywordAuthor | Streptomyces sp 04DH110 | - |
dc.subject.keywordAuthor | antiproliferative agent | - |
dc.subject.keywordAuthor | streptochlorin | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Microbiology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalResearchArea | Microbiology | - |