Isolation and structure determination of streptochlorin, an antiproliferative agent from a marine-derived Streptomyces sp 04DH110 SCIE SCOPUS KCI

DC Field Value Language
dc.contributor.author Shin, Hee Jae -
dc.contributor.author Jeong, Hyun Sun -
dc.contributor.author Lee, Hyi-Seung -
dc.contributor.author Park, Song-Kyu -
dc.contributor.author Kim, Hwan Mook -
dc.contributor.author Kwon, Ho Jeong -
dc.date.accessioned 2020-04-20T11:55:13Z -
dc.date.available 2020-04-20T11:55:13Z -
dc.date.created 2020-01-28 -
dc.date.issued 2007-08 -
dc.identifier.issn 1017-7825 -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/4669 -
dc.description.abstract An antiproliferative agent, streptochlorin, was isolated from the fermentation broth of a marine actinomycete isolated from marine sediment. Phylogenetic analysis of the 16S rRNA gene sequence indicated that the strain belongs to the genus Streptomyces. Bioactivity guided fractionation of the culture extract by solvent partitioning, ODS open flash chromatography, and reversed-phase HPLC gave a pure compound, streptochlorin. Its structure was elucidated by extensive 2D NMR and mass spectral analyses. Streptochlorin exhibited significant antiproliferative activity against human cultured cell lines. -
dc.description.uri 1 -
dc.language English -
dc.publisher KOREAN SOC MICROBIOLOGY & BIOTECHNOLOGY -
dc.subject BACTERIUM -
dc.subject DERIVATIVES -
dc.title Isolation and structure determination of streptochlorin, an antiproliferative agent from a marine-derived Streptomyces sp 04DH110 -
dc.type Article -
dc.citation.endPage 1406 -
dc.citation.startPage 1403 -
dc.citation.title JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY -
dc.citation.volume 17 -
dc.citation.number 8 -
dc.contributor.alternativeName 신희재 -
dc.contributor.alternativeName 이희승 -
dc.identifier.bibliographicCitation JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.17, no.8, pp.1403 - 1406 -
dc.identifier.scopusid 2-s2.0-34548510609 -
dc.identifier.wosid 000249111700025 -
dc.type.docType Article -
dc.identifier.kciid ART001184808 -
dc.description.journalClass 1 -
dc.subject.keywordPlus BACTERIUM -
dc.subject.keywordPlus DERIVATIVES -
dc.subject.keywordAuthor Streptomyces sp 04DH110 -
dc.subject.keywordAuthor antiproliferative agent -
dc.subject.keywordAuthor streptochlorin -
dc.relation.journalWebOfScienceCategory Biotechnology & Applied Microbiology -
dc.relation.journalWebOfScienceCategory Microbiology -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -
dc.description.journalRegisteredClass kci -
dc.relation.journalResearchArea Biotechnology & Applied Microbiology -
dc.relation.journalResearchArea Microbiology -
Appears in Collections:
Marine Resources & Environment Research Division > Marine Biotechnology &Bioresource Research Department > 1. Journal Articles
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