A literature review of bioactive substances for the treatment of periodontitis: In vitro, in vivo and clinical studies
SCIE
SCOPUS
Cited 0 time in
WEB OF SCIENCE
Cited 1 time in
Scopus
-
Title
- A literature review of bioactive substances for the treatment of periodontitis: In vitro, in vivo and clinical studies
-
Author(s)
- Kim, Tae-Hee; Heo, Seong Yeong; Chandika, Pathum; Kim, Young-Mog; Kim, Hyun-Woo; Kang, Hyun Wook; Je, Jae-Young; Qian, Zhong-Ji; Kim, Namwon; Jung, Won-Kyo
- KIOST Author(s)
- Heo, Seong Yeong(허성영)
-
Alternative Author(s)
- 허성영
-
Publication Year
- 2024-01
-
Abstract
- Periodontitis is a common chronic inflammatory disease of the supporting tissues of the tooth that involves a complex interaction of microorganisms and various cell lines around the infected site. To prevent and treat this disease, several options are available, such as scaling, root planning, antibiotic treatment, and dental surgeries, depending on the stage of the disease. However, these treatments can have various side effects, including additional inflammatory responses, chronic wounds, and the need for secondary surgery. Consequently, numerous studies have focused on developing new therapeutic agents for more effective periodontitis treatment. This review explores the latest trends in bioactive substances with therapeutic effects for periodontitis using various search engines. Therefore, this study aimed to suggest effective directions for therapeutic approaches. Additionally, we provide a summary of the current applications and underlying mechanisms of bioactive substances, which can serve as a reference for the development of periodontitis treatments. © 2024
-
ISSN
- 2405-8440
-
URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/45371
-
DOI
- 10.1016/j.heliyon.2024.e24216
-
Bibliographic Citation
- Heliyon, v.10, no.2, 2024
-
Publisher
- Cell Press
-
Keywords
- Bioactive substances; Human gingival fibroblasts; Periodontitis
-
Type
- Article
-
Language
- English
-
Document Type
- Review
- Files in This Item:
-
There are no files associated with this item.
Items in ScienceWatch@KIOST are protected by copyright, with all rights reserved, unless otherwise indicated.