Sesterterpenoids from the sponge Sarcotragus sp. SCIE SCOPUS

Cited 28 time in WEB OF SCIENCE Cited 28 time in Scopus
Title
Sesterterpenoids from the sponge Sarcotragus sp.
Author(s)
Wang, Nan; Song, Jueun; Jang, Kyoung Hwa; Lee, Hyi-Seung; Li, Xian; Oh, Ki-Bong; Shin, Jongheon
KIOST Author(s)
Lee, Hyi Seung(이희승)
Publication Year
2008-04
Abstract
Nineteen new sesterterpenoids and eight known compounds were isolated from the sponge Sarcotragus sp. collected from Soheuksan Island, Korea. The structures of these compounds were determined to be linear sesterterpenoids containing furan or related oxygenated functionalities on the basis of combined chemical and spectroscopic analyses. In addition, the configurations of several previously undetermined compounds were assigned. Several compounds exhibited moderate to major antibacterial activity (compounds 1-3, 17, 18) and cytotoxicity (3, 11, 12) against the K562 cell line and inhibitory activity against isocitrate lyase (6, 13).
ISSN
0163-3864
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/4528
DOI
10.1021/np0780147
Bibliographic Citation
JOURNAL OF NATURAL PRODUCTS, v.71, no.4, pp.551 - 557, 2008
Publisher
AMER CHEMICAL SOC
Subject
MARINE SPONGE; CYTOTOXIC FURANOSESTERTERPENES; ABSOLUTE-CONFIGURATION; GENUS SARCOTRAGUS; PSAMMOCINIA SP; IRCINIA; VARIABILIN; CYCLE; ACIDS
Type
Article
Language
English
Document Type
Article
Publisher
AMER CHEMICAL SOC
Related Researcher
Research Interests

Marine Natural Products,Organic Chemistry,해양천연물,유기화학

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