EXPLORING THE ANTIBIOTIC ARSENAL OF THE SEA: LARGE-SCALE SCREENING OF MARINE BACTERIA IN SEARCH OF POTENTIAL ANTIMICROBIAL COMPOUNDS
- Title
- EXPLORING THE ANTIBIOTIC ARSENAL OF THE SEA: LARGE-SCALE SCREENING OF MARINE BACTERIA IN SEARCH OF POTENTIAL ANTIMICROBIAL COMPOUNDS
- KIOST Author(s)
- Weerasinghe, Pathiranage Jonathan(Weerasinghe, Pathiranage Jonathan); Lee, Young Deuk(이영득); Eom, Tae Yang(엄태양); Gang, Ye Hui(강예희); Marasinghe, Svini Dileepa(Svini); Navindu, Dinara Gajanayaka(Navindu, Dinara Gajanayaka); Oh, Chul Hong(오철홍)
- Alternative Author(s)
- Jonathan; 이영득; 엄태양; 강예희; Svini; Navindu; 오철홍
- Publication Year
- 2023-10-03
- Abstract
- Thegrowingthreatofantibioticresistancehasspurredanurgentneedforthediscoveryofnovelantimicrobialagents.Manyinfectiousdiseasesarebecomingmoredifficulttotreatduetotheemergenceofantibiotic-resistantbacteria.However,marineenvironmentsharbordiverseanduniquemicrobialcommunities,presentingavastuntappedresourcefortheisolationofbioactivecompoundsfromitsmicrobialcommunities.Despitethevastnessoftheoceans,onlyasmallfractionofmarinebacteriahasbeenthoroughlystudiedfortheirantibioticpotential.Manymarinehabitatsremainlargelyunexplored,presentinguntappedresourcesforthediscoveryofnewcompounds.Further,marinebacteriaoftenpossessuniquemetabolicpathwaysandbiosyntheticcapabilitieswhichequipthemwiththeabilitytoproducebioactivecompoundsthatarestructurallydistinctfromthosefoundinterrestrialcounterparts.Thereforethisstudyaimedtoidentifynewantibioticcompoundsfrommarinebacteriabycarefullyscreeningthrough1008marinebacteriafromthebankandadditional48bacteriaisolatedfromthemarineenvironment.Theidentifiedpotentialspeciesholdthepromiseforfurtherdevelopmentastherapeuticagentstoaddressthegrowingchallengeofantibioticresistance.
- Bibliographic Citation
- 13th Asia-Pacific Marine Biotechnology Conference, 2023
- Publisher
- Flinders University
- Type
- Conference
- Language
- English
- Files in This Item:
- There are no files associated with this item.
