Changes in activity of hepatic xenobiotic-metabolizing enzymes of tiger puffer (Takifugu rubripes) exposed to paralytic shellfish poisoning toxins SCIE SCOPUS

Cited 5 time in WEB OF SCIENCE Cited 5 time in Scopus
Title
Changes in activity of hepatic xenobiotic-metabolizing enzymes of tiger puffer (Takifugu rubripes) exposed to paralytic shellfish poisoning toxins
Author(s)
Jeon, J. K.; Lee, J. S.; Shim, W. J.; Aarakawa, O.; Takatani, T.; Honda, S.; Noguchi, T.
KIOST Author(s)
Shim, Won Joon(심원준)
Publication Year
2008-07
Abstract
Attempts were made to examine the effect of paralytic shellfish poisoning toxins (PSP) on hepatic xenobiotic-metabolizing enzymes (XMEs) of tiger puffer (Takifugu rubripes). Two groups of nontoxic tiger fish were analyzed, and one group was fed with a PSP-containing diet (PSP group), and another with a PSP-free diet (control group). After 60 days of feeding, they were compared to each other mainly in terms of the activity of XMEs. Both groups did not differ from each other significantly, in body weight gain, hepatosomatic index, and condition factor Hepatic level of cytochrome P450 was lower in PSP group than control group. NADPH-cytochrome P450 reductase, NADH-cytochrome b5 reductase, and ethoxyresorufin-O-deethylase (EROD) exhibited a reduced activity in PSP group than control group. Statistical analysis found that the activity or concentration of those enzymes correlated with the hepatic level of PSP with r(2)=0.497-0.611.
ISSN
0254-8704
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/4487
Bibliographic Citation
JOURNAL OF ENVIRONMENTAL BIOLOGY, v.29, no.4, pp.599 - 603, 2008
Publisher
TRIVENI ENTERPRISES
Subject
CYTOCHROME-C REDUCTASE; FRESH-WATER PUFFERS; LIVER MICROSOMES; ZOSIMUS-AENEUS; MARINE PUFFER
Keywords
paralytic shellfish poisoning toxin (PSP); puffer fish; Takifugu rubripes; xenobiotic metabolizing enzyme (XME)
Type
Article
Language
English
Document Type
Article
Publisher
TRIVENI ENTERPRISES
Related Researcher
Research Interests

Microplastic pollution,Persistent Organic Pollutants,Oil Pollution,미세플라스틱 오염,잔류성 유기오염물질,유류오염

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