Coscinoderines A–J: Trisubstituted Pyridinium-Containing Norterpenoids Isolated from Coscinoderma bakusi, a Tropical Marine Sponge
SCIE
SCOPUS
Cited 0 time in
WEB OF SCIENCE
Cited 0 time in
Scopus
-
Title
- Coscinoderines A–J: Trisubstituted Pyridinium-Containing Norterpenoids Isolated from Coscinoderma bakusi, a Tropical Marine Sponge
-
Author(s)
- Tran, Huynh Nguyen khanh; Kim, Min Jin; Shin, A Young; Tran, Le Viet ha; Lee, Ji Hoon; Lee, Yeon Ju
- KIOST Author(s)
- Kim, Min Jin(김민진); Shin, A Young(신아영); Lee, Ji Hoon(이지훈); Lee, Yeon Ju(이연주)
-
Alternative Author(s)
- TRAN HUYNH; 김민진; 신아영; Tran Le Viet Ha; 이지훈; 이연주
-
Publication Year
- 2023-08
-
Abstract
- Ten new norterpene alkaloids, coscinoderines A–J (1–10), were isolated from the marine sponge Coscinoderma bakusi. Each coscinoderine contains a 1,2,5-trisubstituted pyridinium moiety bearing a terpene unit at the C-2 position. Their structures were elucidated by analysis of NMR and HRMS data, and the absolute stereochemistry of 4 with a 2-methylbutyl group attached to the nitrogen was determined from a comparison of the calculated and measured ECD spectra. The isolation of coscinoderines expands the repertoire of pyridinium alkaloids isolated from marine sponges.
-
ISSN
- 0163-3864
-
URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/44567
-
DOI
- 10.1021/acs.jnatprod.3c00358
-
Bibliographic Citation
- Journal of Natural Products, v.86, no.9, pp.2145 - 2150, 2023
-
Publisher
- American Chemical Society
-
Keywords
- Assays; Bacteria; Cations; Chemical structure; Granular materials
-
Type
- Article
-
Language
- English
-
Document Type
- Article
- Files in This Item:
-
There are no files associated with this item.
Items in ScienceWatch@KIOST are protected by copyright, with all rights reserved, unless otherwise indicated.