Streptopyrrolidine, an angiogenesis inhibitor from a marine-derived Streptomyces sp KORDI-3973 SCIE SCOPUS

Cited 52 time in WEB OF SCIENCE Cited 56 time in Scopus
Title
Streptopyrrolidine, an angiogenesis inhibitor from a marine-derived Streptomyces sp KORDI-3973
Author(s)
Shin, Hee Jae; Kim, Tae Sik; Lee, Hyi-Seung; Park, Jung Youl; Choi, In-Kwon; Kwon, Ho Jeong
KIOST Author(s)
Lee, Hyi Seung(이희승)
Publication Year
2008-09
Abstract
Streptopyrrolidine, a benzyl pyrrolidine derivative, was isolated as an angiogenesis inhibitor from the fermentation broth of a marine Streptomyces sp. isolated from the deep sea sediment. its structure was elucidated by extensive 2D NMR and mass spectroscopic analyses. Streptopyrrolidine exhibited significant anti-angiogenesis activity. (C) 2008 Elsevier Ltd. All rights reserved.
ISSN
0031-9422
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/4452
DOI
10.1016/j.phytochem.2008.05.020
Bibliographic Citation
PHYTOCHEMISTRY, v.69, no.12, pp.2363 - 2366, 2008
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
Subject
ACID; (S)-4-HYDROXY-2-PYRROLIDINONE
Keywords
Streptomyces sp KORDI-3973; angiogenesis inhibitors; streptopyrrolidine; 5-benzyl-4-hydroxypyrrolidin-2-one; bioactive natural products
Type
Article
Language
English
Document Type
Article
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
Related Researcher
Research Interests

Marine Natural Products,Organic Chemistry,해양천연물,유기화학

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