Preparation and properties of physically cross-linked PVA/pectin hydrogels blended at different ratios for wound dressings
SCIE
SCOPUS
Cited 4 time in
WEB OF SCIENCE
Cited 7 time in
Scopus
-
Title
- Preparation and properties of physically cross-linked PVA/pectin hydrogels blended at different ratios for wound dressings
-
Author(s)
- Oh, Gun-Woo; Choi, Il-Whan; Park, Won Sun; Oh, Chul Hong; Heo, Soo Jin; Kang, Do Hyung; Jung, Won-Kyo
- KIOST Author(s)
- Oh, Chul Hong(오철홍); Heo, Soo Jin(허수진); Kang, Do Hyung(강도형)
-
Alternative Author(s)
- 오철홍; 허수진; 강도형
-
Publication Year
- 2022-03
-
Abstract
- In the present study, we fabricated composite polyvinyl alcohol (PVA) and pectin hydrogels with different blend ratios using a freeze–thaw method. Scanning electron microscopy revealed that the PVA/pectin hydrogels had a porous structure, with the porosity increasing from 82.8% ± 0.5% to 93.2% ± 0.3% with an increase in the pectin content. In addition, with the addition of pectin, the gel fraction of the hydrogel decreased and the swelling ability increased compared with PVA. Of the fabricated hydrogels, the hydrogel with the 9:1 PVA/pectin ratio had the highest compressive strength (684 ± 62 kPa) and G′ value (~1014 kPa). Based on cytotoxicity studies, none of the fabricated hydrogels showed cytotoxicity against HDF or HaCaT cells. These results indicate that varying the pectin content can be used to control the mechanical characterization, porosity, and swelling ability of composite PVA/pectin hydrogels, which are thus promising candidates for use as wound dressings. © 2021 Wiley Periodicals LLC.
-
ISSN
- 0021-8995
-
URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/42057
-
DOI
- 10.1002/app.51696
-
Bibliographic Citation
- Journal of Applied Polymer Science, v.139, no.9, 2022
-
Publisher
- John Wiley & Sons Inc.
-
Keywords
- biocompatibility; biomedical applications; blends; composites; gels
-
Type
- Article
-
Language
- English
-
Document Type
- Article
- Files in This Item:
-
There are no files associated with this item.
Items in ScienceWatch@KIOST are protected by copyright, with all rights reserved, unless otherwise indicated.