Discorhabdins from the Korean Marine Sponge Sceptrella sp. SCIE SCOPUS

Cited 33 time in WEB OF SCIENCE Cited 36 time in Scopus
Title
Discorhabdins from the Korean Marine Sponge Sceptrella sp.
Author(s)
Jeon, Ju-eun; Na, Zeyei; Lung, Misong; Lee, Hyi-Seung; Sim, Chung J.; Nahm, Keepyung; Oh, Ki-Bong; Shin, Jongheon
KIOST Author(s)
Lee, Hyi Seung(이희승)
Publication Year
2010-02
Abstract
Two new pyrroloiminoquinone alkaloids of the discorhabdin class. along with 12 compounds including one previously described synthetic derivative of the same and related skeletal classes, were isolated from the sponge Sceptrella sp., collected from Gageodo, Korea. The structures of these new compounds. designated as (-)-3-dihydrodiscorhabdin D (11) and (-)-discorhabdin Z (12), were determined by combined spectroscopic analyses. Compound 12 possesses all unusual hemiaminal group among the discorhabdin alkaloids. These compounds exhibited moderate to significant cytotoxicity, antibacterial activity, and inhibitory activity against sortase A.
ISSN
0163-3864
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/4139
DOI
10.1021/np9005629
Bibliographic Citation
JOURNAL OF NATURAL PRODUCTS, v.73, no.2, pp.258 - 262, 2010
Publisher
AMER CHEMICAL SOC
Subject
CIRCULAR-DICHROISM SPECTRA; PYRROLOIMINOQUINONE ALKALOIDS; CYTOTOXIC ALKALOIDS; LATRUNCULIA-BREVIS; ZYZZYA-FULIGINOSA; GENUS LATRUNCULIA; NATURAL-PRODUCTS; MAKALUVAMINES; METABOLITES; PIGMENT
Type
Article
Language
English
Document Type
Article
Publisher
AMER CHEMICAL SOC
Related Researcher
Research Interests

Marine Natural Products,Organic Chemistry,해양천연물,유기화학

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