An Enantioselective Synthesis of (+)-Polyoxamic Acid via Phase-Transfer Catalytic Conjugate Addition and Asymmetric Dihydroxylation SCIE SCOPUS
Cited 17 time in
WEB OF SCIENCE
Cited 20 time in
Scopus
- Title
- An Enantioselective Synthesis of (+)-Polyoxamic Acid via Phase-Transfer Catalytic Conjugate Addition and Asymmetric Dihydroxylation
- KIOST Author(s)
- Lee, Yeon Ju(이연주)
- Alternative Author(s)
- 이연주
- Publication Year
- 2011-01-21
- Abstract
- A new enantioselective synthetic method of (+)-polyoxamic acid is reported. (+)-Polyoxamic acid could be obtained in 7 steps with 46% overall yield from diphenylmethyl-glycineimine tert-butyl ester via an enantioselective phase-transfer conjugate addition (99% yield, 96% ee) and an asymmetric dihydroxylation (98% yield, 94% de) as the key reactions.
- ISSN
- 0022-3263
- Bibliographic Citation
- JOURNAL OF ORGANIC CHEMISTRY, v.76, no.2, pp.740 - 743, 2011
- Publisher
- AMER CHEMICAL SOC
- Subject
- ALPHA-AMINO-ACIDS; POLYOXAMIC ACID; BIOLOGICAL-ACTIVITY; STEREOSELECTIVE-SYNTHESIS; 3,4-DIEPIPOLYOXAMIC ACID; EFFICIENT SYNTHESIS; ALKYLATION; SERINE; AGENTS; ROUTE
- Type
- Article
- Language
- English
- Document Type
- Article
- Files in This Item:
- There are no files associated with this item.
