Acetylthiocholine (ATC) - Cleaving cholinesterase (ChE) activity as a potential biomarker of pesticide exposure in the Manila clam, Ruditapes philippinarum, of Korea SCIE SCOPUS

Cited 14 time in WEB OF SCIENCE Cited 15 time in Scopus
Title
Acetylthiocholine (ATC) - Cleaving cholinesterase (ChE) activity as a potential biomarker of pesticide exposure in the Manila clam, Ruditapes philippinarum, of Korea
Author(s)
Choi, Jin Young; Yu, Jun; Yang, Dong Beom; Ra, Kongtae; Kim, Kyung Tae; Hong, Gi Hoon; Shin, Kyung Hoon
KIOST Author(s)
Choi, Jin Young(최진영)Ra, Kong Tae(나공태)Kim, Kyung Tae(김경태)
Publication Year
2011-04
Abstract
The acetylthiocholine (ATC) - cleaving cholinesterase (ChE) activity in Manila clam, which is widely distributed throughout the coastal environment of Korea, was assayed as a potentially useful biomarker of organophosphorous pesticides (OPs). A clear dose-response relationship was determined between inhibited ChE in adductor muscle of clams and four OPs (methidathion, chlorpyrifos, diazinon, IBP) which are heavily used OPs in Korea. The measured EC50-24 h values of methidathion, chlorpyrifos, diazinon, and IBP for Ruditapes philippinarum were 7.16 mu g l(-1), 0.34 mg l(-1), 3.01 mg l(-1), and 3.41 mg l(-1), respectively. In field studies, ChE activity in Manila clams collected from 23 stations in the mid-western coastal region demonstrated spatial variation with statistical differences. These results suggest that ChE activity in R. philippinarum is a potential biomarker for assessing organophosphorous pesticide contamination in coastal environments. (C) 2011 Elsevier Ltd. All rights reserved.
ISSN
0141-1136
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/3876
DOI
10.1016/j.marenvres.2010.12.007
Bibliographic Citation
MARINE ENVIRONMENTAL RESEARCH, v.71, no.3, pp.162 - 168, 2011
Publisher
ELSEVIER SCI LTD
Subject
POLYCYCLIC AROMATIC-HYDROCARBONS; ACETYLCHOLINESTERASE ACTIVITY; MYTILUS-GALLOPROVINCIALIS; ADAMUSSIUM-COLBECKI; TAPES-PHILIPPINARUM; CRASSOSTREA-GIGAS; JOINT ACTION; IN-VITRO; EDULIS; INHIBITION
Keywords
Cholinesterase; Biomarker; Chlorpyrifos; IBP; Organophosphorous pesticides (OPs); Manila clam; Ruditapes philippinarum
Type
Article
Language
English
Document Type
Article
Publisher
ELSEVIER SCI LTD
Related Researcher
Research Interests

Management of marine environment,Marine pollution,Trace metal(Heavy metal),해양환경관리,해양오염,미량금속(중금속)

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