Radical Scavenging Activity of Poncirus trifoliata Extracts and Their Inhibitory Effect Against Hydrogen Peroxide Induced Cell Damage SCIE SCOPUS KCI

DC Field Value Language
dc.contributor.author Eom, Sung-Hwan -
dc.contributor.author Heo, Soo-Jin -
dc.contributor.author Lee, Dae-Sung -
dc.contributor.author Lee, Myung-Suk -
dc.contributor.author Kim, Young-Man -
dc.contributor.author Jung, Won-Kyo -
dc.contributor.author Kim, Young-Mog -
dc.date.accessioned 2020-04-20T07:43:49Z -
dc.date.available 2020-04-20T07:43:49Z -
dc.date.created 2020-01-28 -
dc.date.issued 2011-06 -
dc.identifier.issn 1738-2203 -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/3860 -
dc.description.abstract Poncirus trifoliata was evaluated for antioxidant potential by several radical-scavenging assays, including 1,1-diphenyl-2-picrylhydrazyl, superoxide, hydroxyl, and alkyl radicals, using electron spin resonance technique. P trifoliata extracts were prepared by using water and methanol, partitioning with different organic solvents. Among the tested samples, water extract and dichloromethane fraction evidenced relatively higher scavenging activities than those of other samples on reactive radicals and have high amount of antioxidant component such as flavonoids (8.5 +/- 0.3 and 8.3 +/- 0.2 mg rutin equivalents/g dry weight basis) and proanthocyanidin (2.6 +/- 0.3 and 2.8 +/- 0.5 mg catechin equivalents/g dry weight basis), respectively. Moreover, the water extract showed significantly high enhancement of cell viability against hydrogen peroxide-induced oxidative damage as well as reduction in the hydrogen peroxide-induced intracellular reactive oxygen species on CCL. 13 cell line. These results indicate that P trifoliate exerts various antioxidant effects against several reactive radicals and hydrogen peroxide-mediated cell damage. Thus, P trifoliate could be a potential therapeutic modality for the treatment or prevention of several diseases associated with oxidative stress. -
dc.description.uri 1 -
dc.language English -
dc.publisher KOREAN SOC APPLIED BIOLOGICAL CHEMISTRY -
dc.subject ANTIOXIDANT ACTIVITY -
dc.subject ENZYMATIC EXTRACTS -
dc.subject SUPEROXIDE -
dc.subject APOPTOSIS -
dc.subject GROWTH -
dc.subject FRUIT -
dc.subject ASSAY -
dc.subject CATECHINS -
dc.subject CAPACITY -
dc.subject NECROSIS -
dc.title Radical Scavenging Activity of Poncirus trifoliata Extracts and Their Inhibitory Effect Against Hydrogen Peroxide Induced Cell Damage -
dc.type Article -
dc.citation.endPage 487 -
dc.citation.startPage 479 -
dc.citation.title JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY -
dc.citation.volume 54 -
dc.citation.number 3 -
dc.contributor.alternativeName 허수진 -
dc.identifier.bibliographicCitation JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY, v.54, no.3, pp.479 - 487 -
dc.identifier.doi 10.3839/jksabc.2011.074 -
dc.identifier.scopusid 2-s2.0-79960532025 -
dc.identifier.wosid 000292996300024 -
dc.type.docType Article -
dc.identifier.kciid ART001567024 -
dc.description.journalClass 1 -
dc.subject.keywordPlus ANTIOXIDANT ACTIVITY -
dc.subject.keywordPlus ENZYMATIC EXTRACTS -
dc.subject.keywordPlus SUPEROXIDE -
dc.subject.keywordPlus APOPTOSIS -
dc.subject.keywordPlus GROWTH -
dc.subject.keywordPlus FRUIT -
dc.subject.keywordPlus ASSAY -
dc.subject.keywordPlus CATECHINS -
dc.subject.keywordPlus CAPACITY -
dc.subject.keywordPlus NECROSIS -
dc.subject.keywordAuthor antioxidant -
dc.subject.keywordAuthor cell damage -
dc.subject.keywordAuthor electron spin resonance -
dc.subject.keywordAuthor Poncirus trifoliata -
dc.subject.keywordAuthor radical scavenging -
dc.relation.journalWebOfScienceCategory Food Science & Technology -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -
dc.description.journalRegisteredClass kci -
dc.relation.journalResearchArea Food Science & Technology -
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Jeju Research Institute > Jeju Bio Research Center > 1. Journal Articles
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