Monanchocidins B-E: Polycyclic Guanidine Alkaloids with Potent Antileukemic Activities from the Sponge Monanchora pulchra SCIE SCOPUS

DC Field Value Language
dc.contributor.author Makarieva, Tatyana N. -
dc.contributor.author Tabakmaher, Ksenya M. -
dc.contributor.author Guzii, Alla G. -
dc.contributor.author Denisenko, Vladimir A. -
dc.contributor.author Dmitrenok, Pavel S. -
dc.contributor.author Shubina, Larisa K. -
dc.contributor.author Kuzmich, Alexandra S. -
dc.contributor.author Lee, Hyi-Seung -
dc.contributor.author Stonik, Valentin A. -
dc.date.accessioned 2020-04-20T07:43:27Z -
dc.date.available 2020-04-20T07:43:27Z -
dc.date.created 2020-01-28 -
dc.date.issued 2011-09 -
dc.identifier.issn 0163-3864 -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/3818 -
dc.description.abstract New unusual polycyclic guanidine alkaloids monanchocidins B-E (2-5) along with monanchocidin A (1), which we recently described, were isolated from the Far-Eastern marine sponge Monanchora pulchra. Their structures were established using spectroscopic data and chemical transformations. Compounds 1-5 show potent cytotoxic activities against HL-60 human leukemia cells with IC(50) values of 540, 200, 110, 830, and 650 nM, respectively. -
dc.description.uri 1 -
dc.language English -
dc.publisher AMER CHEMICAL SOC -
dc.subject CRAMBE-CRAMBE -
dc.subject PTILOMYCALIN-A -
dc.subject BATZELLA SP -
dc.subject UNGUIFERA -
dc.subject CRAMBESCIDIN-800 -
dc.subject DERIVATIVES -
dc.subject HIV-1 -
dc.title Monanchocidins B-E: Polycyclic Guanidine Alkaloids with Potent Antileukemic Activities from the Sponge Monanchora pulchra -
dc.type Article -
dc.citation.endPage 1958 -
dc.citation.startPage 1952 -
dc.citation.title JOURNAL OF NATURAL PRODUCTS -
dc.citation.volume 74 -
dc.citation.number 9 -
dc.contributor.alternativeName 이희승 -
dc.identifier.bibliographicCitation JOURNAL OF NATURAL PRODUCTS, v.74, no.9, pp.1952 - 1958 -
dc.identifier.doi 10.1021/np200452m -
dc.identifier.scopusid 2-s2.0-80053177148 -
dc.identifier.wosid 000295100400017 -
dc.type.docType Article -
dc.description.journalClass 1 -
dc.subject.keywordPlus CRAMBE-CRAMBE -
dc.subject.keywordPlus PTILOMYCALIN-A -
dc.subject.keywordPlus BATZELLA SP -
dc.subject.keywordPlus UNGUIFERA -
dc.subject.keywordPlus CRAMBESCIDIN-800 -
dc.subject.keywordPlus DERIVATIVES -
dc.subject.keywordPlus HIV-1 -
dc.relation.journalWebOfScienceCategory Plant Sciences -
dc.relation.journalWebOfScienceCategory Chemistry, Medicinal -
dc.relation.journalWebOfScienceCategory Pharmacology & Pharmacy -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -
dc.relation.journalResearchArea Plant Sciences -
dc.relation.journalResearchArea Pharmacology & Pharmacy -
Appears in Collections:
Marine Resources & Environment Research Division > Marine Biotechnology &Bioresource Research Department > 1. Journal Articles
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