Evaluation of antioxidant properties of a new compound, pyrogallol-phloroglucinol-6,6 '-bieckol isolated from brown algae, Ecklonia cava SCIE SCOPUS KCI

Cited 22 time in WEB OF SCIENCE Cited 23 time in Scopus
Title
Evaluation of antioxidant properties of a new compound, pyrogallol-phloroglucinol-6,6 '-bieckol isolated from brown algae, Ecklonia cava
Author(s)
Kang, Sung-Myung; Lee, Seung-Hong; Heo, Soo-Jin; Kim, Kil-Nam; Jeon, You-Jin
KIOST Author(s)
Heo, Soo Jin(허수진)
Publication Year
2011-12
Abstract
In this study, antioxidant and free radical scavenging activities of the natural antioxidative compound, pyrogallol-phloroglucinol-6,6'-bieckol (PPB) isolated from brown algae, Ecklonia cova was assessed in vitro by measuring the radical scavenging activities (DPPH, alkyl, hydroxyl, and superoxide) using electron spin resonance (ESR) spectrometry, intracellular reactive oxygen species (ROS) scavenging activity, and DNA damage assay. According to the results of these experiments, the scavenging activity PPB against difference radicals was in the following order: DPPH, alkyl, hydroxyl, and superoxide radicals (IC50; 0.90, 2.54, 62.93 and 109.05 mu M). The antioxidant activities of PPB were higher than that of the commercial antioxidant, ascorbic acid. Furthermore, PPB effectively inhibited DNA damage induced by H2O2. These results suggest that the natural antioxidative compound. PPB, can be used by the natural food industry.
ISSN
1976-1457
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/3784
DOI
10.4162/nrp.2011.5.6.495
Bibliographic Citation
NUTRITION RESEARCH AND PRACTICE, v.5, no.6, pp.495 - 502, 2011
Publisher
KOREAN NUTRITION SOC
Subject
RADICAL-SCAVENGING CAPACITY; MEDICINAL-PLANTS; TEA CATECHINS; FLAVONOIDS; DAMAGE; ASSAY; ESR
Keywords
Ecklonia cava; brown algae; pyrogallol-phloroglueinol-6,6 ' -bieckol; antioxidant
Type
Article
Language
English
Document Type
Article
Publisher
KOREAN NUTRITION SOC
Related Researcher
Research Interests

Marine Biotechnology,Marine Natural Products,Bioactivities,해양생물공학,해양천연물학,생리활성

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