Nortriterpene Glycosides of the Sarasinoside Class from the Sponge Lipastrotethya sp. SCIE SCOPUS

Cited 14 time in WEB OF SCIENCE Cited 15 time in Scopus
Title
Nortriterpene Glycosides of the Sarasinoside Class from the Sponge Lipastrotethya sp.
Author(s)
Lee, Jung-Ho; Jeon, Ju-eun; Lee, Yeon-Ju; Lee, Hyi-Seung; Sim, Chung J.; Oh, Ki-Bong; Shin, Jongheon
KIOST Author(s)
Lee, Yeon Ju(이연주)Lee, Hyi Seung(이희승)
Publication Year
2012-07
Abstract
Five new nortriterpene glycosides, along with eight known compounds of the sarasinoside class, were isolated from the tropical sponge Lipastrotethya sp. collected from Chuuk, Micronesia. The structures of these new compounds, designated as sarasinosides N-R (9-13), were determined by combined spectroscopic and chemical methods. The aglycone portions of 10-13 were found to be unprecedented among nortriterpeneoids on the basis of extensive NMR analyses. Several of these compounds exhibited cytotoxicity against A549 and K562 cell lines as well as weak inhibitory activity. against Na+/K+-ATPase.
ISSN
0163-3864
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/3494
DOI
10.1021/np300297d
Bibliographic Citation
JOURNAL OF NATURAL PRODUCTS, v.75, no.7, pp.1365 - 1372, 2012
Publisher
AMER CHEMICAL SOC
Subject
MARINE NATURAL-PRODUCTS; ASTEROPUS-SARASINOSUM; TRITERPENOID SAPONINS; OLIGOGLYCOSIDES; GALACTOSIDES; GROWTH; ASSAY; C1; B1; A1
Type
Article
Language
English
Document Type
Article
Publisher
AMER CHEMICAL SOC
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