Neuroprotective Effects of Nannochloropsis oculata Against AAPH-induced Oxidative DNA Damage in HT22 Cells SCIE SCOPUS
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kim, Kil-Nam | - |
| dc.contributor.author | Cha, Seon-Heui | - |
| dc.contributor.author | Kim, Eun-A | - |
| dc.contributor.author | Kang, Min-Cheol | - |
| dc.contributor.author | Yang, Hye-Mi | - |
| dc.contributor.author | Kim, Min-Joo | - |
| dc.contributor.author | Yang, Hye-Young | - |
| dc.contributor.author | Roh, Seong Woon | - |
| dc.contributor.author | Jung, Won-Kyo | - |
| dc.contributor.author | Heo, Soo-Jin | - |
| dc.contributor.author | Kim, Daekyung | - |
| dc.contributor.author | Jeon, You-Jin | - |
| dc.contributor.author | Oda, Tatsuya | - |
| dc.date.accessioned | 2020-04-20T06:51:23Z | - |
| dc.date.available | 2020-04-20T06:51:23Z | - |
| dc.date.created | 2020-01-28 | - |
| dc.date.issued | 2012-08-15 | - |
| dc.identifier.issn | 1811-7775 | - |
| dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/3478 | - |
| dc.description.abstract | Water extracts of Nannochloropsis oculata (WNO) were investigated to determine whether they exhibited neuroprotective effects against oxidative-stress-induced cell damage by 2,2'-Azobis (2-amidinopropane) dihydrochloride (AAPH) in murine hippocampus neuronal (HT22) cells. We observed that WNO exhibited scavenging effects on hydroxyl and alkyl radicals as well as on intracellular Reactive Oxygen Species (ROS). As a consequence, WNO reduced AAPH-induced cell death, the fraction of sub-G(1) cells and DNA damage in HT22 cells. The results of this study demonstrate that WNO could be used as an alternative to more toxic synthetic antioxidants as an additive in food, pharmaceutical and cosmetic preparations. | - |
| dc.description.uri | 1 | - |
| dc.language | English | - |
| dc.publisher | ASIAN NETWORK SCIENTIFIC INFORMATION-ANSINET | - |
| dc.subject | MICROALGAE NAVICULA-INCERTA | - |
| dc.subject | ANTIOXIDANT ACTIVITIES | - |
| dc.subject | ENZYMATIC EXTRACTS | - |
| dc.subject | ISHIGE OKAMURAE | - |
| dc.subject | ECKLONIA-CAVA | - |
| dc.subject | STRESS | - |
| dc.subject | TOXICITY | - |
| dc.subject | ACID | - |
| dc.subject | INDUCTION | - |
| dc.subject | RELEVANCE | - |
| dc.title | Neuroprotective Effects of Nannochloropsis oculata Against AAPH-induced Oxidative DNA Damage in HT22 Cells | - |
| dc.type | Article | - |
| dc.citation.endPage | 534 | - |
| dc.citation.startPage | 527 | - |
| dc.citation.title | INTERNATIONAL JOURNAL OF PHARMACOLOGY | - |
| dc.citation.volume | 8 | - |
| dc.citation.number | 6 | - |
| dc.contributor.alternativeName | 허수진 | - |
| dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF PHARMACOLOGY, v.8, no.6, pp.527 - 534 | - |
| dc.identifier.doi | 10.3923/ijp.2012.527.534 | - |
| dc.identifier.scopusid | 2-s2.0-84866084391 | - |
| dc.identifier.wosid | 000316977400010 | - |
| dc.type.docType | Article | - |
| dc.description.journalClass | 1 | - |
| dc.subject.keywordPlus | MICROALGAE NAVICULA-INCERTA | - |
| dc.subject.keywordPlus | ANTIOXIDANT ACTIVITIES | - |
| dc.subject.keywordPlus | ENZYMATIC EXTRACTS | - |
| dc.subject.keywordPlus | ISHIGE OKAMURAE | - |
| dc.subject.keywordPlus | ECKLONIA-CAVA | - |
| dc.subject.keywordPlus | STRESS | - |
| dc.subject.keywordPlus | TOXICITY | - |
| dc.subject.keywordPlus | ACID | - |
| dc.subject.keywordPlus | INDUCTION | - |
| dc.subject.keywordPlus | RELEVANCE | - |
| dc.subject.keywordAuthor | Neuroprotection | - |
| dc.subject.keywordAuthor | water extract | - |
| dc.subject.keywordAuthor | Nannochloprosis oculata | - |
| dc.subject.keywordAuthor | oxidative stress | - |
| dc.subject.keywordAuthor | HT22 cells | - |
| dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
- Appears in Collections:
- Jeju Research Institute > Jeju Bio Research Center > 1. Journal Articles
- Files in This Item:
- There are no files associated with this item.
